Dispensing Categories of Medicinal Products

Definition The dispensing of licensed medicines is strictly regulated by law in many countries. Drugs may be available by prescription (prescription-only), nonprescription, and over-the-counter. Typical dispensing points are pharmacies, drugstores and doctors’ offices, provided that self-dispensing is permitted by the canton. Category E drugs may also be sold in the retail trade, for example in … Dispensing Categories of Medicinal Products

Angelica Balm

Products Angelica balms are available in pharmacies and drugstores, among other places. The original recipe goes back to the German midwife Ingeborg Stadelmann. Today, several variations exist. Structure and properties An angelica balsam is a semi-solid preparation for external use, which consists of a lipophilic base (e.g. beeswax, shea butter, lanolin, almond oil, olive oil), … Angelica Balm

Eucalyptus Oil Capsules

Products Eucalyptus oil capsules have been approved in many countries since 2016 (Sibrovita N). In Germany, they have been on the market since the 1990s (Aspecton Eukaps). Structure and properties Eucalyptus oil is an essential oil obtained by steam distillation and subsequent rectification from the fresh leaves or branch tips of various 1,8-cineole-rich eucalyptus species. … Eucalyptus Oil Capsules

Darunavir

Products Darunavir is commercially available as film-coated tablets and as an oral suspension (Prezista). It has been approved in many countries since 2006. In 2016, a fixed-dose combination with cobicistat was approved (Rezolsta film-coated tablets). In 2018, generic versions of the tablets entered the market. Structure and properties Darunavir (C27H37N3O7S, Mr = 547.7 g/mol) is … Darunavir

Endothelin Receptor Antagonists

Products Endothelin receptor antagonists are commercially available in the form of film-coated and dispersible tablets. The first agent in this group to be approved was bosentan (Tracleer) in the United States in 2001 and in the EU and Switzerland in 2002. Effects Antivasoconstrictive Reduce pulmonary and systemic vascular resistance Higher blood flow volume without increasing … Endothelin Receptor Antagonists

Febuxostat

Products Febuxostat is commercially available in the form of film-coated tablets (Adenuric). It was approved in many countries in 2016. It was registered in the EU in 2008 and in the US in 2009 (US: Uloric). Structure and properties Febuxostat (C16H16N2O3S, Mr = 316.4 g/mol), unlike allopurinol, does not have a purine structure. It is … Febuxostat

Silver Nitrate Rods

Products A silver nitrate stick looks like a large matchstick with a gray silver nitrate head. Potassium nitrate is included as an excipient. The sticks are commonly used in medical treatment. For example, the sticks are available from Laguba (http://www.laguba.ch). Structure and properties Silver nitrate (AgNO3, Mr = 169.9 g/mol) exists as colorless, translucent crystals … Silver Nitrate Rods

Dinoprostone

Products Dinoprostone is commercially available as a vaginal insert and vaginal tablet (Propess, Prostin E2). It is also available as a vaginal gel and vaginal suppository in some countries. Dinoprostone has been approved in many countries since 1986. Structure and properties Dinoprostone (C20H32O5, Mr = 352.5 g/mol) corresponds to the natural prostaglandin E2. It exists … Dinoprostone

Methylnaltrexone

Products Methylnaltrexone is commercially available as a solution for injection (Relistor). It has been approved in many countries since 2009. Structure and properties Methylnaltrexone (C21H26NO4, Mr = 356.4 g/mol) is an -methylated naltrexone. It is present in drugs as methylnaltrexone bromide. Effects Methylnaltrexone (ATC A06AH01) counteracts constipation caused by opioids. The effects are due to … Methylnaltrexone

Combined Flu and Cold Remedies

Products Among the best-known combined flu and cold remedies in many countries are NeoCitran, Pretuval, and Vicks Medinait. In addition, other products exist such as Fluimucil Flu Day & Night. In other countries, different products are commonly used, such as Grippostad in Germany or Theraflu in the United States. Ingredients Typical ingredients include: Sympathomimetics such … Combined Flu and Cold Remedies

Mefloquine

Products Mefloquine is commercially available in the form of film-coated tablets (generic: mephaquine). The active ingredient was approved in many countries in 1984. Distribution of the original Lariam (Roche) was discontinued in 2014 for commercial reasons. Structure and properties Mefloquine (C17H16F6N2O, Mr = 378.3 g/mol) is a fluorinated quinoline and piperidine derivative and an analog … Mefloquine

Venetoclax

Products Venetoclax was approved in the US and EU in 2016 and in many countries in 2018 in film-coated tablet form (Venclyxto, Venclexta). Structure and properties Venetoclax (C45H50ClN7O7S, Mr = 868.4 g/mol) exists as a light to dark yellow powder that is sparingly soluble in water. Effects Venetoclax (ATC L01XX52) has antitumor and cytotoxic properties. … Venetoclax