Products Antiandrogens are mainly commercially available in the form of tablets, capsules, and injectables. Among the first steroidal agents was cyproterone acetate, which was patented in the 1960s. Flutamide was the first non-steroidal agent to be approved in the 1980s. Structure and properties A distinction is made between antiandrogens with a steroidal structure (like the … Antiandrogens
Products Proligeston is commercially available as an injection suspension. It has been approved in many countries since 1979. Structure and properties Proligestone (C24H34O4, Mr = 386.5 g/mol) is a synthetic progestin. Effects Proligestone (ATCvet QG03DA90) has progestogenic and antigonodotrophic properties. Indications For estrus regulation in bitches, cats, and ferrets.
Menopause usually occurs in women between the ages of 45 and 60. During this time, the body’s production of sex hormones decreases and the ability to reproduce recedes. At the same time, but also four to five years earlier, more or less pronounced complaints such as hot flashes, sweating and emotional changes can cause problems. … Menopause: Climacteric
Products Vaginal suppositories are commercially available as drugs and medical devices. Listed below are some active ingredients which are administered vaginally: Estrogens: estriol Progestins: progesterone Antifungals: Econazole, ciclopirox Antiparasitics: Metronidazole, Clindamycin Antiseptics: Povidone–iodine, formerly boric acid. Probiotics: Lactobacilli The egg-shaped vaginal suppositories are also called ovules (singular ovulum). Structure and properties Vaginal suppositories are dosage … Vaginal Suppositories
Active ingredients (selection) Progestins Estrogens Herbal gynecologics Monk’s pepper Black cohosh
Products Estradiol is commercially available in tablet, transdermal patch, transdermal gel, vaginal ring, and vaginal tablet forms, among others. It is also combined fixed with progestogens. Structure and properties Estradiol (C18H24O2, Mr = Mr = 272.4 g/mol) exists as a white crystalline powder that is practically insoluble in water. Synthetic estradiol is bioidentical with human … Estradiol
Symptoms Menopausal symptoms are very individual and vary from woman to woman. The most common possible disorders include: Cycle irregularities, change in menstruation. Vasomotor disorders: Flushes, night sweats. Mood swings, irritability, aggressiveness, sensitivity, sadness, difficulty concentrating, anxiety, fatigue. Sleep disorders Changes in skin, hair and mucous membranes: hair loss, vaginal atrophy, vaginal dryness, dry skin, … Menopausal Symptoms
Indications Inhibition of labor during pregnancy to prevent preterm delivery Active ingredients Minerals: Magnesium (e.g. magnesium diasporal). Calcium channel blockers: Nifedipine (Adalat, generic, off-label). Progestins: Progesterone (Utrogestan) Probiotics: Lactobacilli (vaginal suppositories to prevent infections). Oxytocin antagonists: Atosiban (Tractocile). Sympathomimetics: Hexoprenaline (Gynipral) Fenoterol (no indication in many countries). Salbutamol (Ventolin, no indication in many countries). Other … Labor Inhibitors
Products Gestodene is marketed in many countries exclusively in combination with ethinyl estradiol in the form of dragées and film-coated tablets as an oral contraceptive (“pill”). It has been approved in many countries since 1986. Structure and properties Gestodene (C21H26O2, Mr = 310.4 g/mol) exists as a white to yellowish crystalline powder that is practically … Gestodene
Products Drospirenone is commercially available as a fixed combination with ethinyl estradiol for contraception in the form of film-coated tablets (Yasmin, Yasminelle, YAZ, generics, auto-generics). Drospirenone is also used in combination with estradiol for hormone replacement therapy (Angeliq). Bayer’s originals Yasmin, Yasminelle and YAZ will go off the market in many countries in December 2021. … Drospirenone
Products Ulipristal acetate was approved in the EU in 2009 and in the United States in 2010 (ellaOne, film-coated tablets). In many countries, ulipristal acetate was registered in late 2012. Since February 1, 2016, the morning-after pill has been available in pharmacies without a doctor’s prescription after a consultation and dispensing documentation (see also under … Ulipristal Acetate
Symptoms Gestational diabetes is a glucose intolerance that is first discovered during pregnancy and is common, occurring in approximately 1-14% of all pregnancies. Typical symptoms of diabetes mellitus such as thirst, frequent urination, and fatigue may occur, but are considered rare. Nonspecific complaints such as increased susceptibility to urinary tract infections may indicate gestational diabetes. … Gestational Diabetes