Products Carboplatin is commercially available as an infusion solution (paraplatin, generic). It has been approved in many countries since 1986. Structure and properties Carboplatin (C6H12N2O4Pt, Mr = 371.3 g/mol) is a platinum compound. It exists as a colorless crystalline powder that is sparingly soluble in water. Carboplatin is structurally related to cisplatin, the first platinum … Carboplatin
Products Topotecan is commercially available in capsule form and as a lyophilizate (Hycamtin, generic). It has been approved in many countries since 1996. Structure and properties Topotecan (C23H23N3O5, Mr = 421.4 g/mol) is present in the drug as topotecan hydrochloride. It is a semisynthetic derivative of camptothecin, a plant alkaloid derived from the tree. Effects … Topotecan
Structure and properties Etoposide (C29H32O13, Mr = 588.6 g/mol) is a derivative of podophyllotoxin. It exists as a white crystalline powder that is practically insoluble in water. The substance is weakly hygroscopic. Effects Etoposide (ATC L01CB01) is cytostatic. It inhibits topoisomerase II and blocks the cell cycle at stage G2. Indications Acute myeloid leukemia Hodgkin’s … Etoposide
Chronic lung diseases Other risk factors include chronic lung diseases such as tuberculosis, where residual tissue damage can develop into so-called scar carcinomas. Genetic factors If one parent falls ill, the personal risk increases 2-3 times. Forms of lung carcinoma Non small cell lung cancer (NSCLC) This includes squamous cell carcinoma, which is mainly located … Chronic lung diseases | Lung Cancer
Synonyms Lung-Ca, lung carcinoma, bronchial carcinoma, small cell bronchial carcinoma, squamous cell carcinoma, large cell bronchial carcinoma, adenocarcinoma, pancost tumor, NSCLC : Non small cell lung cancer, SCLC: Small cell lung cancer, oat cell cancer Definition Lung cancer is a malignant mass in the lungs, originating in the tissue of the bronchi. Different types of … Lung Cancer
Causes Many different influences are involved in the development of lung cancer, but there are some factors that increase the personal risk of developing lung cancer. The development of lung cancer is not yet completely understood. As with all cancers, there is an uncontrolled division of cells and an unchecked destructive growth. It is assumed … Causes | Lung Cancer
The diagnosis of cancer confronts many patients with the question of life and survival. The question “how long do I have left?” burns very quickly under the nails of most of those affected, since the diagnosis “cancer” is still associated with certain death. However, nowadays only a few types of cancer mean certain non-survival. The … Lung Cancer Prognosis
Tumor stage and spread Tumors tend to spread and form further metastases. They spread to the surrounding lymph nodes or via the blood to distant organs. In patients with lung cancer, metastases are mainly found in the surrounding lymph nodes of the thorax as well as in the liver, brain, adrenal glands and skeleton, especially … Tumor stage and spread | Lung Cancer Prognosis
Age and gender The age and gender as well as the general physical and mental condition of the affected person also play a role in the probability of survival. Women have a higher survival rate after 5 years than men. Patients in poor general physical condition are often unable to derive a positive effect from … Age and gender | Lung Cancer Prognosis
