Symptoms Skin tears on the fingers – known as rhagades – are deep, cleft-like, and often keratinized lesions that extend into the dermis of the skin and occur mainly near the fingernails at the tips of the fingers. They may also occur on the back of the hand. Despite their small size, the skin tears … Skin Cracks on the Fingers
Symptoms Local skin reactions such as itching, inflammation, redness, and blistering occur acutely, especially at the sites of contact with the trigger. In the chronic stage, dry, scaly and cracked skin is often observed, e.g. in the form of chronic hand eczema. Affected areas include the hands, abdomen and earlobes. The rash can also appear … Metal Allergy
Symptoms Nummular eczema (from Latin , coin) is an inflammatory skin disease that manifests itself in sharply defined, coin-shaped rashes that primarily affect the extensor sides of the legs, arms, and trunk. The areas are weeping, inflamed (reddened), and may become dry, crusted, and itchy. Unlike cutaneous fungus, the lesions are filled in and do … Nummular Eczema
Symptoms Irritant contact dermatitis is a common inflammatory condition of the skin. It often occurs on the hands and manifests in the following possible signs and symptoms: Redness Swellings Dry skin Scaling, often between the fingers Itching, burning, pain, tightness, tingling. Increased sensitivity, for example, to alcohol in disinfectants. Skin thickening Painful tears Crusts Erosions … Irritant Contact Dermatitis
Symptoms Usually beginning before the age of 20, the appearance of white patches is completely asymptomatic; the foci themselves exhibit neither itching nor scaling, are often bizarrely configured, and occasionally have darker pigmentation around the edges. A hereditary predisposition exists in one third (approx. 35%) of affected individuals. The spread is extremely variable, it can … Vitiligo (White Spot Disease)
Symptoms Psoriasis is a chronic inflammatory, benign, and noninfectious skin disease. It manifests as symmetrical (bilateral), sharply demarcated, bright red, dry, raised plaques covered by silvery scales. Typically affected areas are the elbows, knees, and scalp. Itching, a burning sensation and pain are other symptoms, and scratching further aggravates the condition. Psoriasis can also affect … Psoriasis Causes and Treatment
Symptoms Rosacea is a chronic inflammatory skin disorder of the face that typically affects the cheeks, nose, chin, and central forehead symmetrically (Figure). The skin around the eyes is left out. It occurs more often in people with fair skin and in middle age, but it can occur in any skin type and at any … Rosacea Causes and Treatment
Products Pimecrolimus is commercially available as a cream (Elidel). It has been approved in many countries since 2003. Structure and properties Pimecrolimus (C43H68ClNO11, Mr = 810.5 g/mol) is a lipophilic macrolactam derivative of ascomycin, an ethyl analog of tacrolimus. It exists as a white crystalline powder that is insoluble in water. Effects Pimecrolimus (ATC D11AX15) … Pimecrolimus
Symptoms So-called dyshidrotic eczema manifests itself in itchy, non-reddened vesicles or blisters (bullae) that may appear on the sides of the fingers, on the palms of the hands, and also on the feet. The rash is often bilateral and symmetrical. The vesicles or blisters are filled with edema fluid (“water blisters”) and are located in … Dyshidrotic Eczema
Products Topical calcineurin inhibitors are commercially available in many countries as ointments and creams (Protopic, Elidel). They have been approved in many countries since 2001 and 2003, respectively. Effects The active ingredients (ATC D11AH) have anti-inflammatory and immunomodulatory properties. The effects are based on inhibition of the calcium-dependent phosphatase calcineurin. This reduces T-cell activation and … Topical Calcineurin Inhibitors
Products Tacrolimus is commercially available for external use as an ointment in two concentrations (Protopic). It has been approved in many countries since 2001. Structure and properties Tacrolimus (C44H69NO12 – H2O, Mr = 822.0 g/mol) is a complex macrolide formed by the fungus-like bacterium. It is present in drugs as tacrolimus monohydrate, white crystals, or … Topical Tacrolimus
Symptoms Atopic dermatitis, or neurodermatitis, is a noncontagious, chronic inflammatory skin disease that causes episodes of red, rough, dry or weeping, crusted and scaly skin. Eczema can occur all over the body and is typically accompanied by severe itching. Patients have dry skin. In infants, the disease begins on the scalp and cheeks. Depending on … Atopic Dermatitis: Eczema
