Toxic megacolon is a life-threatening complication of various bowel diseases. The colon becomes massively enlarged and septic-toxic inflammation occurs. What is toxic megacolon? Toxic megacolon is defined as acute dilatation of the colon with clinically prominent inflammation of the colon. Various diseases and, in particular, diseases of the colon may be considered as causes. However, … Toxic Megacolon: Causes, Symptoms & Treatment
Introduction Ulcerative colitis is one of the chronic inflammatory bowel diseases. As the name suggests, the disease has a chronic course. This means that it accompanies most sufferers throughout their lives. In the case of chronic diseases, many patients are therefore faced with the question of whether the disease has an influence on life expectancy … Life expectancy in ulcerative colitis
What influence does the therapy have on life expectancy? The therapy of ulcerative colitis significantly influences the disease activity. Without treatment, colitis is in most cases much more aggressive than with treatment. Drug therapy can even achieve remission in a certain proportion of patients, i.e. the disease comes to a complete stop. However, the disease … What influence does the therapy have on life expectancy? | Life expectancy in ulcerative colitis
Inheritance in Hirschsprung’s disease Hirschsprung’s disease is an inherited disease. It is not possible to determine a specific gene as the trigger of the disease. Depending on which gene is affected, the disease is inherited autosomal-dominantly or autosomal-recessively. Autosomal-dominant means that if the newborn child inherits a diseased gene from one parent, it is automatically … Inheritance in Hirschsprung’s disease | Hirschsprung’s disease
What is the life expectancy with Hirschsprung’s disease? Whether or not life expectancy is limited with Hirschsprung’s disease depends on the accompanying malformations that also affect a patient. In 70% of cases, the affected children are completely healthy except for Hirschsprung’s disease. Life expectancy is not restricted and is the same as for other children. … What is the life expectancy with Hirschsprung’s disease? | Hirschsprung’s disease
Definition Hirschsprung’s disease is a rare congenital disease. It occurs with a frequency of about 1 : 3. 000 – 5. 000 affected newborns. The disease manifests itself in the gastrointestinal tract. In one part of the intestine, nerve cells and nerve cell bundles (ganglia) are missing. This is known as aganglionosis. In addition to … Hirschsprung’s disease
Symptoms The symptoms of Hirschsprung’s disease are already apparent in the newborn. The child is conspicuous by a strongly inflated abdomen. On the other hand, the first thin stool (technically called meconium) should be excreted within the first 24 to 48 hours. In newborns with Hirschsprung’s disease, the first stool is given late or usually … Symptoms | Hirschsprung’s disease
Therapy of Hirschsprung’s disease Treatment of Hirschsprung’s disease cannot be conservative, but must be carried out surgically. In the beginning, an artificial bowel outlet is created surgically (anus praeter), so that the bowel can be emptied. The artificial bowel outlet is created in front of the site affected by the disease. This allows the disease … Therapy of Hirschsprung’s disease | Hirschsprung’s disease
Complications Since the stool often fails to pass in newborns with Hirschsprung’s disease, an artificial stool evacuation must be performed. If this is not carried out in time, a complication known as necrotizing enterocolitis can occur, which is an acute, life-threatening disease of the gastrointestinal tract. If the accumulated stool is excessively colonized with bacteria, … Complications | Hirschsprung’s disease
Definition Toxic megacolon is an acute, life-threatening clinical picture, which can occur as a complication of other intestinal diseases, such as Crohn’s disease, ulcerative colitis, Chagas disease, and pseudomembranous colitis. Toxic megacolon is an enlargement of the colon accompanied by severe colitis. Those affected often come to the emergency room with acute, severe abdominal pain … Toxic megacolon
Symptoms of a toxic megacolon The main symptom with which the affected persons present themselves in the emergency room is very severe abdominal pain and a defensive tension in the abdominal area, which presents itself to the examiner as a stomach as hard as a board. The pain is accompanied by high fever and a … Symptoms of a toxic megacolon | Toxic megacolon
Possible complications of a toxic megacolon Some possible complications are known to exist in the Toxic Megacolon. One possibility is that of an intestinal rupture. In this case, the severely damaged intestine breaks open and the intestinal contents enter the abdominal cavity, which can lead to peritonitis. Furthermore, there is a risk that the affected … Possible complications of a toxic megacolon | Toxic megacolon
