Products Eptinezumab is in the development phase and is not yet commercially available. Structure and properties Eptinezumab is an IgG1 monoclonal antibody directed against CGRP. Effects Eptinezumab reduces the number of migraine attacks. The effects are due to binding of the antibody to CGRP, the calcitonin gene-related peptide. CGRP is a neuropeptide that plays an … Eptinezumab
Introduction Naratriptan is a drug in the group of drugs called triptans. Triptans belong to the well-tolerated and effective drugs against migraine due to a special mechanism of action at the 5 HT receptor. Indications Naratriptan has its main use in the treatment of migraine. Here, migraine accompanied by an aura can be treated just … Naratriptan
Side effects Like any drug, Naratriptan has risks when taken and side effects that must be considered before taking it. In general, however, Naratriptan is well tolerated. Possible side effects include mild nausea and discomfort. Since Naratriptan works by constricting blood vessels, constrictions in other blood vessels may also occur. This would lead to pressure-like … Side effects | Naratriptan
Dosage Naratriptan is taken in a dosage of 2.5 mg as a tablet. The tablet can be taken independently of meals. Initially the treatment is started with 1x 2.5 mg. If there is no improvement in symptoms, a second film-coated tablet can be taken 4 hours after the first one. The maximum dose of 2x … Dosage | Naratriptan
Products Almotriptan is commercially available in the form of film-coated tablets (Almogran). It has been approved in many countries since 2004. Structure and properties Almotriptan (C17H25N3O2S, Mr = 335.5 g/mol) is present in drugs as almotriptan-D,L-hydrogenmalate, a white to slightly yellowish crystalline powder that is soluble in water. Effects Almotriptan (ATC N02CC05) has vasoconstrictive, analgesic, … Almotriptan for Migraine Headache
Definition Medication overuse involves using self-purchased or physician-prescribed medications for too long, too much, or too frequently. The duration of therapy prescribed by a healthcare professional or by the professional and patient information is exceeded, the maximum single or daily dose is too high because of a dose increase, or the dosing interval is too … Medication Overuse
Products Lorcaserin is commercially available in the form of film-coated tablets (Belviq). It was approved in the United States on June 27, 2012. It is not currently registered in many countries. Structure and properties Lorcaserin (C 11 H 14 ClN, M r = 195.7 g/mol) is present in drugs as lorcaserin hydrochloride and hemihydrate, a … Lorcaserin
Products Frovatriptan is commercially available in the form of film-coated tablets (Menamig). It has been approved in many countries since 2004. Structure and properties Frovatriptan (C14H17N3O, Mr = 243.3 g/mol) is present in drugs as frovatriptan succinate monohydrate, a white powder that is soluble in water. It is an indole derivative and structurally related to … Frovatriptan
Products Moclobemide is commercially available in the form of film-coated tablets (Aurorix, generics). It has been approved in many countries since 1990. Structure and properties Moclobemide (C13H17ClN2O2, Mr = 268.74 g/mol) is a morpholine and chlorinated benzamide derivative. It exists as a white to yellowish white or reddish powder and is sparingly soluble in water. … Moclobemide
Symptoms Migraine occurs in attacks. It may announce itself up to three days before an attack with various precursors (prodromes). These include, for example: Mood changes Fatigue Hunger Frequent yawning Irritability Aura may occur before the headache phase in up to about one-third of patients: Visual disturbances such as flickering lights, dots or lines, facial … Migraine Headache
Symptoms Menstrual migraine is a migraine without aura that typically occurs 2 days before to the 3rd day of menstruation Two forms are distinguished, first, menstrual migraine that occurs exclusively on these days and second, migraine that also, but not exclusively, occurs on these days. Causes The causes are not yet fully understood. Estrogen withdrawal … Menstrual Migraine
Products Lasmiditan was approved in the United States in 2019 in film-coated tablet form (Reyvow). Structure and properties Lasmiditan (C19H18F3N3O2, Mr = 377.4 g/mol) is present in the drug as lasmiditanhemisuccinate, a white crystalline powder that is sparingly soluble in water. It is a piperidine and pyridine derivative and has no indole structure. Effects Lasmiditan … Lasmiditan
