Lodoxamide

Products Lodoxamide is commercially available in the form of eye drops (Alomide). The drug is not registered in many countries. Structure and properties Lodoxamide (C11H6ClN3O6, Mr = 311.6 g/mol) is present in the drug as lodoxamide trometamol, a white crystalline powder that is soluble in water. See also under trometamol. Effects Lodoxamide (ATC S01GX05) has … Lodoxamide

Ketorolac

Products Ketorolac commercially available in the form of film-coated tablets, as a solution for injection (Tora-Dol), and as eye drops (Acular, generic). It has been approved in many countries since 1992. Structure and properties Ketorolac (C15H13NO3, Mr = 255.7 g/mol) is present in drugs in the form of the salt ketorolactrometamol (= ketorolactromethamine), see also … Ketorolac

Auxiliary Materials

Definition On the one hand, drugs contain the active ingredients that mediate the pharmacological effects. On the other hand, they consist of excipients, which are used for the production or to support and regulate the drug effect. Placebos, which consist only of excipients and contain no active ingredients, are an exception. Excipients can be of … Auxiliary Materials

Dinoprost

Products Dinoprost is commercially available as a veterinary drug as a solution for injection (Dinolytic, Enzaprost). It has been approved in many countries since 1981. Structure and properties Dinoprost (C20H34O5, Mr = 354.5 g/mol) exists as dinoprost trometamol, a white crystalline powder that is very soluble in water. It corresponds to the natural prostaglandin F2α. … Dinoprost

Active Ingredient Salts

Structure and properties Many active pharmaceutical ingredients are present in the drug as organic salts. This means that the active ingredient is ionized and its charge is neutralized by a counterion (English ). For example, naproxen is present in the over-the-counter pain reliever as a sodium salt. In this form, it is referred to as … Active Ingredient Salts

Triethanolamine

Products Triethanolamine is found as an excipient in pharmaceuticals such as emulsions, creams and gels, and personal care products, among others. It is also known as trolamine in the pharmaceutical industry. It should not be confused with trometamol. Structure and properties Triethanolamine (C6H15NO3, Mr = 149.2 g/mol) is present as a clear, viscous, colorless to … Triethanolamine

Dexketoprofen

Products Dexketoprofen is commercially available as film-coated tablets and as a solution for injection (Ketesse). It has been approved in many countries since 2000. In 2017, a fixed combination with tramadol was registered; see Tramadol Dexketoprofen (Skudexa). Structure and properties Dexketoprofen (C16H14O3, Mr = 254.3) is the active -enantiomer of ketoprofen, which exists as a … Dexketoprofen

Trometamol

Products Trometamol is found as an excipient in drugs, for example, in liquid and semisolid dosage forms. It should not be confused with triethanolamine (trolamine). Structure and properties Trometamol (C4H11NO3, Mr = 121.1 g/mol) exists as a white crystalline powder or as colorless crystals and is readily soluble in water. It contains both hydroxyl groups … Trometamol