Childhood Vaccinations: Which ones, when, and why?

Which vaccinations are important for babies and children? Vaccinations protect against serious diseases that can be potentially serious and even fatal – for example, measles, mumps, rubella, diphtheria and whooping cough. Unlike in many other countries, there is no mandatory vaccination in Germany, but there are detailed vaccination recommendations. These are developed by the Permanent … Childhood Vaccinations: Which ones, when, and why?

Vaccines: What does “X percent effective” mean?

95 percent effectiveness, 80 percent effectiveness – or only 70 percent effectiveness? The data on the newly developed Corona vaccines first make many people aware that vaccinations vary in effectiveness – and that no vaccination offers 100 percent protection. Already, the first people would rather not be vaccinated with the “less effective” vaccines from AstraZeneca … Vaccines: What does “X percent effective” mean?

Cystic Fibrosis: Causes and Treatment

Symptoms In cystic fibrosis (CF, cystic fibrosis), different organ systems are affected, resulting in a heterogeneous clinical picture with symptoms of varying severity: Lower respiratory tract: Chronic cough with viscous mucus formation, obstruction, recurrent infectious diseases, e.g., with , inflammation, remodeling of the lungs (fibrosis), pneumothorax, respiratory insufficiency, shortness of breath, wheezing, oxygen deficiency. Upper … Cystic Fibrosis: Causes and Treatment

Sputnik V

Products Sputnik V is a Covid-19 vaccine developed in Russia and the first vaccine from this group to be registered on August 11, 2020 (Gamaleya National Center of Epidemiology and Microbiology). The name is derived from the Sputnik satellite, which was the first satellite placed in Earth orbit by the Soviet Union in 1957. Sputnik … Sputnik V

Oclacitinib

Products Oclacitinib is commercially available in the form of film-coated tablets for dogs (Apoquel). It has been approved in many countries since 2014. Structure and properties Oclacitinib (C15H23N5O2S, Mr = 337.4 g/mol) is present in the drug as oclacitinib maleate. Effects Oclacitinib (ATCvet QD11AH90) has anti-inflammatory, antiallergic, and antipruritic properties. The effects are due to … Oclacitinib

AZD1222

Products AZD1222 has been in the registration phase in the EU and many countries since the beginning of October 2020 as part of a rolling review and is not yet commercially available. The vaccine was developed at Oxford University’s Jenner Institute, spin-off Vaccitech and AstraZeneca. Efficacy and safety are being evaluated in studies involving up … AZD1222

Abatacept

Products Abatacept is commercially available as an injection and infusion preparation (Orencia). It was approved in the United States in 2005 and in the EU and many countries in 2007. Structure and properties Abatacept is a recombinant fusion protein with the following components: Extracellular domain of CTLA-4 (cytotoxic T-lymphocyte-associated protein 4). Modified Fc domain of … Abatacept

Mosquito Bites

Symptoms Possible symptoms after a mosquito bite include local reactions such as: Itching Wheal formation, swelling, induration Redness, feeling of warmth Inflammation Due to the skin lesion, there is a risk of infection. Usually mosquito bites are self-limiting and disappear after a few days on their own. However, a mosquito bite can also cause swelling … Mosquito Bites

Thiomersal

Products Thiomerasal has been used as an excipient in pharmaceuticals, especially in liquid dosage forms such as eye drops and vaccines. It is rarely used today because of the potential adverse effects. The substance is also known as thimerosal. Structure and properties Thiomerasal (C9H9HgNaO2S, Mr = 404.8 g/mol) exists as a white crystalline powder and … Thiomersal

Tacrolimus (Protopic, Prograf): Drug Effects, Side Effects, Dosage and Uses

Products Tacrolimus is commercially available in the form of capsules, sustained-release capsules, sustained-release tablets, as a concentrated solution for infusion, as granules, and as an ointment (Prograf, generic, Advagraf, Protopic, generic, Modigraf). It has been approved in many countries since 1996. This article refers to oral use; see also Topical Tacrolimus (Protopic Ointment). Structure and … Tacrolimus (Protopic, Prograf): Drug Effects, Side Effects, Dosage and Uses

Chickenpox Vaccination

Products Chickenpox vaccine is commercially available as an injectable in many countries (e.g., Varivax). It can also be combined fixed with the MMR vaccine (= MMRV vaccine). Structure and properties This is a live attenuated vaccine containing varicella-zoster virus of the OKA/Merck strain grown in human cells. This strain was developed in Japan in the … Chickenpox Vaccination