Medical history (history of illness) represents an important component in the diagnosis of hyperuricemia or gout.
Family history
- Is gout common in your family?
- Are there any hereditary diseases in your family?
Social anamnesis
Current medical history/systemic medical history (somatic and psychological complaints).
- Do you suffer from joint pain? Which joints are affected?
- Is the affected joint overheated, swollen and limited in function?
- Do you have a fever? If so, for how long and what is the temperature?
- Have you noticed any joint deformities?
- Have you noticed bursitis (mostly at the elbow)?
- Were there any triggers for the pain?
- Physical exertion?
- Accident?
- When did the pain occur?
Vegetative anamnesis including nutritional anamnesis.
- Are you overweight? Please tell us your body weight (in kg) and height (in cm).
- Do you eat a balanced diet?
- Were there any triggers for the pain?
- Do you consume a lot of foods high in purine (meat) and/or fructose?
- Do you drink alcohol? If so, what drink(s) and how many glasses per day?
Self history incl. medication history.
- Pre-existing conditions (renal disease, tumor disease).
- Surgery (condition after intra-articular injection/injection into a joint).
- Radiotherapy
- Allergies
- Environmental history (beryllium, lead)
Medication history
- Acetylsalicylic acid (ASA) (<1,000 mg/die); the lower the dose, the higher the risk of gout:
- < 325 mg/die: 81% (OR=1.81, 95% CI 1.30-2.51).
- ≤ 100 mg/die: 95% (OR=1.91, 95% CI 1.32-2.85)
- Antiphlogistics, nonsteroidal (oxyphenbutazone, phentylbutazone).
- ATP citrate lyase (ACL) inhibitor (bempedoic acid).
- Beta blocker
- Diazoxide
- Diuretics
- Loop diuretics (etacrynic acid, furosemide, piretanide, torasemide).
- Thiazide diuretics (chlortalidone, hydrochlorothiazide (HCT), xipamide).
- Ethambutol (antibiotic/tuberculostat).
- Immunosuppressants (ciclosporin (cyclosporin A))
- L-dopa
- Nicotinic acid
- Parathyroid hormone analogue (teriparatide)
- Tuberculostatics (pyrazinamide)
- Cytostatics
