Medical history (medical history) represents an important component in the diagnosis of andropause (male menopause). Family history Social history Is there any evidence of psychosocial stress or strain due to your family situation? Current medical history/systemic history (somatic and psychological complaints). Do you notice a decreased ability to perform? Have you noticed a decrease in … Male Menopause, Andropause: Medical History
Congenital malformations, deformities, and chromosomal abnormalities (Q00-Q99). Klinefelter syndrome – genetic disorder with mostly sporadic inheritance: numerical chromosomal aberration (aneuploidy) of the sex chromosomes (gonosomal anomaly) occurring only in boys or Men occurs; in the majority of cases characterized by a supernumerary X chromosome (47, XXY); clinical picture: large stature and testicular hypoplasia (small testis), … Male Menopause, Andropause: Or something else? Differential Diagnosis
The following are the most important diseases or complications that can be caused by andropause (male menopause) as well: Clinical picture of hypogonadism (mod. by). Blood, hematopoietic organs – immune system (D50-D90). Anemia (anemia) Endocrine, nutritional, and metabolic diseases (E00-E90). Obesity (overweight) (29.5 vs. 26.7). Hypogonadism (gonadal hypofunction) – low testosterone levels are associated with … Male Menopause, Andropause: Consequential Diseases
A comprehensive clinical examination is the basis for selecting further diagnostic steps: General physical examination – including blood pressure, pulse, body weight, height [current body weight versus age-related ideal weight: increase in body weight with increase in body fat percentage; decreasing muscle strength; visceral adiposity* ; determination of body mass index as well as waist-to-hip … Male Menopause, Andropause: Examination
Obligatory medical device diagnostics. Transrectal prostate sonography – ultrasound examination of the prostate through the rectum. Electrical impedance analysis (measurement of body compartments/body composition) – to determine body fat, extracellular body mass (blood and tissue fluid), body cell mass (muscle and organ mass), and total body water including body mass index (BMI, body mass index) … Male Menopause, Andropause: Diagnostic Tests
Many men in the middle stage of life show symptoms similar to those experienced by women in menopause (menopause). As diverse as the tasks of androgens – the male sex hormones – are, as diverse can be the symptoms and complaints that arise or are caused by a lack of androgens – essentially by testosterone. … Male Menopause, Andropause: Symptoms, Complaints, Signs
General measures Aim for normal weight! Determination of BMI (body mass index, body mass index) or body composition using electrical impedance analysis. BMI ≥ 25 → participation in a medically supervised weight loss program. Falling below the BMI lower limit (from the age of 55: 23; from the age of 65: 24) → Participation in … Male Menopause, Andropause: Therapy
Laboratory parameters of the 1st order – obligatory laboratory tests. Hormone diagnostics Total testosterone (see “Important note” below). SHBG (sex hormone binding globulin) [with advancing age SHBG ↑ → bioavailable (metabolically active) testosterone ↓] LH (luteinizing hormone) Prolactin TSH IGF-1 (insulin-like growth factor), DHEA-S dehydroepiandrosterone sulfate), estradiol, if applicable. Small blood count Atherosclerosis parameters: Total … Male Menopause, Andropause: Lab Test
Therapeutic target To compensate for the partial androgen deficit of the aging male. It should be noted that male hypogonadism (symptomatic hypogonadism/gonadal hypofunction) is defined as follows [EAU guideline]. Total testosterone serum level < 12 nmol/l or 3.5 ng/ml (350 ng/dl) plus Organ functions and quality of life impaired by androgen deficiency. At total testosterone … Male Menopause, Andropause: Drug Therapy
