Zika Virus Infection

Zika Virus Infection: Symptoms, Complaints, Signs

The following symptoms and complaints may indicate Zika virus infection: Main symptoms Aphtae on the lip Arthralgias (joint pain) – especially in the wrists and ankles, knees (about 2/3 of patients). Pronounced feeling of illness Emesis (vomiting) Fever Hemospermia (blood in the semen) Skin rash (maculopapular exanthema/ blotchy rash appearing with small nodules). Conjunctivitis (conjunctivitis). … Zika Virus Infection: Symptoms, Complaints, Signs

Zika Virus Infection: Causes

Pathogenesis (disease development) Zika virus is one of the flaviviruses. They are transmitted by mosquitoes of the genus Aedes (Aedes aegypti (Egyptian tiger mosquito; main vector), Aedes africanus, Aedes luteocephalus, Aedes vittatus, Aedes furcider). If one has been bitten by an infected mosquito, the virus first attacks dendritic cells. From there, it spreads throughout the … Zika Virus Infection: Causes

Zika Virus Infection: Therapy

General measures Observance of the general hygiene measures! Due to the fever: Bed rest and physical rest (even with only a low fever). Fever below 38.5 °C does not necessarily need to be treated! (Exceptions: Children prone to febrile convulsions; old, weakened people; patients with a weakened immune system). For fever from 39 ° C … Zika Virus Infection: Therapy

Zika Virus Infection: Complications

The following are the most important diseases or complications that may be contributed to by Zika virus infection: Congenital malformations, deformities, and chromosomal abnormalities (Q00-Q99). Arthrogryposis multiplex congenita – contractures of muscles leading to deformities of joints; most commonly affecting the extremities and especially the feet (common: clubfoot) Lissencephaly (severe malformation of the brain). Microcephaly … Zika Virus Infection: Complications

Zika Virus Infection: Examination

A comprehensive clinical examination is the basis for selecting further diagnostic steps: General physical examination – including blood pressure, pulse, body temperature, body weight, body height. Inspection (viewing) Skin [maculopapular exanthema/ blotchy rash occurring with small nodules]. Mucous membranes [aphthae on the lip] Eyes [conjunctivitis (conjunctivitis)] Abdomen (abdomen) Shape of the abdomen? Skin color? Skin … Zika Virus Infection: Examination

Zika Virus Infection: Test and Diagnosis

Laboratory parameters 1st order – obligatory laboratory tests. Serum or plasma IgM and IgG serum antibodies to Zika virus [blood collection: from day 8-27 after symptom onset; only antibody detection is possible after the 4th week of illness]Caution: cross-reactivity with other flaviviruses (e.g., TBE, yellow fever, or dengue virus) in ELISA and IIFT. Only a … Zika Virus Infection: Test and Diagnosis

Zika Virus Infection: Drug Therapy

Therapeutic target Symptom relief Therapy recommendations Symptomatic therapy: analgesics/pain relievers, antipyretics/antipyretics. Caveat (Warning): reluctance to administer NSAIDs (non-steroidal anti-inflammatory drugs), as they may induce hemorrhagic fever in other flaviviruses.

Zika Virus Infection: Diagnostic Tests

Mandatory medical device diagnostics in gravidity (pregnancy). Vaginal sonography (ultrasound examination using an ultrasound probe inserted into the vagina) or abdominal sonography (every 4 weeks) – for diagnosis in pregnancy with proven ZikV(Zika virus) infection [intrauterine short stature, microcephaly, enlarged ventricles, lissencephaly (severe maldevelopment of the brain), and arthrogryposis (congenital joint stiffness)]* . Fetal ultrasound … Zika Virus Infection: Diagnostic Tests

Zika Virus Infection: Prevention

To prevent Zika virus infection, attention must be paid to reducing individual risk factors. Behavioral risk factors Bite of mosquito of the genus Aedes (Aedes aegypti (Egyptian tiger mosquito; main vector), Aedes africanus, Aedes luteocephalus, Aedes vittatus, Aedes furcider)Note: Tiger mosquitoes are diurnal mosquitoes and are distributed worldwide in the tropics and subtropics, as well … Zika Virus Infection: Prevention

Zika Virus Infection: Medical History

Medical history represents an important component in the diagnosis of Zika virus infection. Family history What is the general health of your family members? Social history Have you been abroad recently? If so, where exactly? Current medical history/systemic history (somatic and psychological complaints). What symptoms have you noticed? How long have these symptoms been present? … Zika Virus Infection: Medical History

Zika Virus Infection: Or something else? Differential Diagnosis

Infectious and parasitic diseases (A00-B99). Chikungunya fever – disease caused by chikungunya virus and transmitted by mosquitoes. Dengue fever (viral hemorrhagic fever (VHF)) Yellow fever Influenza (flu) Morbilli (measles) Rubella (rubella)