Membranoproliferative Glomerulonephritis: Medical History

Medical history (history of illness) represents an important component in the diagnosis of membranoproliferative glomerulonephritis. Family history Social history Vegetative anamnesis Increase in weight Changes in the body (bloated) Changes in the urine Symptoms such as headaches, which may indicate hypertension (high blood pressure) Self history including medication history. Pre-existing conditions Presence of malignant (malignant) … Membranoproliferative Glomerulonephritis: Medical History

Membranoproliferative Glomerulonephritis: Or something else? Differential Diagnosis

Blood, hematopoietic organs-immune system (D50-D90). Schönlein-Henoch purpura (age <20 years). Genitourinary system (kidneys, urinary tract – reproductive organs) (N00-N99). Other forms of glomerulonephritis Benign familial hematuria (synonym: thin basement membrane nephropathy) – isolated, familial persistent glomerular hematuria (blood in the urine) and minimal proteinuria (excretion of protein in the urine) with normal renal function.

Membranoproliferative Glomerulonephritis: Examination

A comprehensive clinical examination is the basis for selecting further diagnostic steps: General physical examination – including blood pressure, pulse, body weight, height; further: Inspection (viewing). Skin, mucous membranes, and sclerae (white part of the eye) [leading symptoms: generalized edema (water retention occurring all over the body); morning swelling of eyelids, face, lower legs] Auscultation … Membranoproliferative Glomerulonephritis: Examination

Membranoproliferative Glomerulonephritis: Test and Diagnosis

1st order laboratory parameters – obligatory laboratory tests. Small blood count Urine status (rapid test for: pH, leukocytes, nitrite, protein, glucose, ketone, urobilinogen, bilirubin, blood), sediment, urine culture if necessary (pathogen detection and resistogram, i.e. testing suitable antibiotics for sensitivity/resistance). Assessment of erythrocyte morphology [dysmorphic erythrocytes (malformed red blood cells): especially acanthocytes (= erythrocytes with … Membranoproliferative Glomerulonephritis: Test and Diagnosis

Membranoproliferative Glomerulonephritis: Drug Therapy

Therapeutic target Avert deterioration of renal function. Therapy recommendations No effective therapeutic option exists for this form of glomerulonephritis. However, a therapeutic attempt can be made with the platelet aggregation inhibitors acetylsalicylic acid and dipyramidol. The data situation for this is, however, still very little convincing! Immunosuppressants also failed to gain acceptance. A combination of … Membranoproliferative Glomerulonephritis: Drug Therapy

Membranoproliferative Glomerulonephritis: Micronutrient Therapy

An at-risk group indicates the possibility that the disease may be associated with the risk of vital nutrient (micronutrient) deficiency. The complaint nephrotic syndrome indicates vital nutrient (micronutrient) deficiency for: Calcium Iron Copper Zinc A risk group indicates the possibility that the disease may be associated with the risk of vital substance deficiency (micronutrients). The … Membranoproliferative Glomerulonephritis: Micronutrient Therapy

Membranoproliferative Glomerulonephritis: Symptoms, Complaints, Signs

The following symptoms and complaints may indicate membranoproliferative glomerulonephritis: Leading symptoms Generalized edema – water retention occurring throughout the body. Proteinuria – increased excretion of protein in the urine. Hypoproteinemia – too little protein in the blood. Derailment of fat metabolism Associated symptoms Hypertension (high blood pressure) Microhematuria (microscopically visible: blood in the urine).

Membranoproliferative Glomerulonephritis: Causes

Pathogenesis (disease development) The pathogenesis of membranoproliferative glomerulonephritis is not fully understood. Immune complexes are thought to be deposited in different areas of the kidney, subendothelially (type I) or intramembranously (type II). A primary form can be distinguished from a secondary form. In the primary form, no underlying disease can be diagnosed. Etiology (causes) Behavioral … Membranoproliferative Glomerulonephritis: Causes

Membranoproliferative Glomerulonephritis: Therapy

General measures Nicotine restriction (refraining from tobacco use). Review of permanent medication due topossible effect on the existing disease. Avoidance of drug use: Heroin Vaccinations The following vaccinations are advised, as infection can often lead to worsening of the present disease: Flu vaccination Hepatitis B vaccination Pneumococcal vaccination Regular checkups Regular medical checkups Nutritional medicine … Membranoproliferative Glomerulonephritis: Therapy