Breast Cancer (Mammary Carcinoma): Adjuvant Therapy for Older Women

Radiotherapy In patients without significant comorbidities, radiotherapy (radiation therapy) should usually follow BET (breast-conserving therapy) as well as mastectomy (removal of the mammary glands) with advanced tumor stage. Patients limited by comorbidities (concomitant diseases) should receive limited therapy. Endocrine therapy Systemic endocrine therapy (hormone therapy) can be given without restriction to older patients limited by … Breast Cancer (Mammary Carcinoma): Adjuvant Therapy for Older Women

Breast Cancer (Mammary Carcinoma): Or something else? Differential Diagnosis

Skin and subcutaneous (L00-L99). Atopic eczema (neurodermatitis)* . Chronic dermatoses* (including acne, Lyme disease (infectious disease caused by the bacterium Borrelia burgdorferi), herpes zoster (shingles), herpes simplex, psoriasis (psoriasis), urticaria (hives), bullous autoimmune dermatoses/blistering disease ) Cutaneous mycosis* (fungal disease of the skin). Panniculitis* – localized inflammation of the subcutaneous fat tissue; the overlying skin … Breast Cancer (Mammary Carcinoma): Or something else? Differential Diagnosis

Breast Cancer (Mammary Carcinoma): Complications

The following are the most important diseases or complications that may be contributed to by breast carcinoma: Endocrine, nutritional, and metabolic diseases (E00-E90). Diabetes mellitus – incidence (frequency of new cases) is moderately increased for postmenopausal women with breast carcinoma Hypercalcemia (calcium excess) due to tumor hypercalcemia (tumor-induced hypercalcemia, TIH). Cardiovascular System (I00-I99). Lymphedema (after … Breast Cancer (Mammary Carcinoma): Complications

Breast Cancer (Mammary Carcinoma): Examination

General From the aspect of breast carcinoma, there are three examination aspects: Women with an increased risk of breast cancer due to family history: they must be submitted to a so-called multimodal intensified early detection at an early stage. The following examinations are necessary because of the difficulty in assessing breast tissue, which is denser … Breast Cancer (Mammary Carcinoma): Examination

Breast Cancer (Mammary Carcinoma): Test and Diagnosis

For clarification of a suspicious palpatory finding, priority is given to methods of medical device diagnostics, mammography (X-ray examination of the breast), sonography (ultrasound), magnetic resonance imaging (MRI) if necessary, and for histological (fine tissue) clarification, punch biopsy (tissue sample). Note: Every palpatory and/or sonographic suspicious finding must be clarified by histological examination (punch biopsy). … Breast Cancer (Mammary Carcinoma): Test and Diagnosis

Breast Cancer (Mammary Carcinoma): Drug Therapy

Prevention Drug prevention in women at increased risk of breast cancer regarding [4; S3 guideline: see below]: Invasive carcinomas Preinvasive changes Lobular carcinoma in situ (LCIS). Ductal carcinoma in situ (DCIS) and Intraductal atypical hyperplasia (ADH). Therapy target To improve prognosis in women at risk of developing a hormone-sensitive tumor (positivity of estrogen (ER) and … Breast Cancer (Mammary Carcinoma): Drug Therapy

Breast Cancer (Mammary Carcinoma): Diagnostic Tests

Mandatory medical device diagnostics. Mammography (X-ray examination of the breast) – currently the only method that detects precancerous/early stages; examination of both mammaries mandatoryNote: With increased mammographic density, a combination of 2-D and 3-D mammography (tomosynthesis: see below Digital Breast Tomosynthesis (DBT)), with only a slight increase in radiation exposure, can achieve a significant increase … Breast Cancer (Mammary Carcinoma): Diagnostic Tests

Breast Cancer (Mammary Carcinoma): Therapy of Metastatic Breast Carcinoma

General: Cure is the exception for distant metastases (daughter tumors that form near the primary tumor). Therapeutic Objective Achieve: As high a quality of life as possible Freedom from pain and symptoms Therapy Adjusts according to The individual wishes of the patient The type of metastases The symptoms The age The concomitant diseases The hormone … Breast Cancer (Mammary Carcinoma): Therapy of Metastatic Breast Carcinoma

Breast Cancer (Mammary Carcinoma): Causes

Pathogenesis (disease development) It is not exactly clear which causes are responsible for the development of breast carcinoma. In most cases, the disease occurs spontaneously.Even more than for the familial forms of breast carcinoma, genetic defects are responsible for the spontaneous development of this carcinoma. In 40 percent of patients with breast carcinoma, a p53 … Breast Cancer (Mammary Carcinoma): Causes

Breast Cancer (Mammary Carcinoma): Micronutrient Therapy

Within the framework of micronutrient medicine (vital substances), the following vital substances (micronutrients) are used to prevent (prevent) breast cancer. Folic acid Vitamin D Lutein, lycopene, zeaxanthin In the context of micronutrient medicine (vital substances), the following vital substances (macro- and micronutrients) are used for supportive therapy. Gamma-linolenic acid (GLA) Case reports continue to report … Breast Cancer (Mammary Carcinoma): Micronutrient Therapy

Breast Cancer (Mammary Carcinoma): Surgical Therapy

General With few exceptions (e.g., high-risk patients with a family history who may have preventive surgery), breast cancer therapy today consists of a combination of different therapies (surgery, radiotherapy (radiation therapy), chemotherapy, antihormone therapy). Preoperative imaging, punch or vacuum biopsy diagnostics in combination with: Histology (fine tissue examination), Grading (assessment of the degree of differentiation … Breast Cancer (Mammary Carcinoma): Surgical Therapy