Sweating (Hyperhidrosis): Or something else? Differential Diagnosis

Congenital malformations, deformities, and chromosomal abnormalities (Q00-Q99).

  • Vitia* (congenital heart defects).

Endocrine, nutritional, and metabolic diseases (E00-E90).

  • Obesity* (obesity).
  • Acromegaly* (giant growth)
  • Andropause (male menopause)
  • Diabetes mellitus* (diabetes)
  • Hyperthyroidism* (hyperthyroidism)
  • Hypoglycemia* (hypoglycemia; reactive, so not diabetic).
  • Menopause* (climacteric; menopause in women).

Skin and subcutaneous tissue (L00-L99)

  • Eccrine and vascular tumors* *
  • Organoid nevi* * (multiform skin lesions congenital or manifesting in early childhood).
  • Palmoplantar keratoses (keratinization disorders affecting the palms (=palmar) and soles (=plantar)).
  • Pachydermoperiostosis* * (form of primary hypertrophic osteoarthropathy), in ulcer environment, at the amputation stump.
  • Ross syndrome* * (synonyms: familial anhidrosis, anhidrosis syndrome) – neurological-dermatological disorder associated with a simultaneous occurrence of hypo- or anhidrosis (decreased or abolished sweat secretion), pupillotonia (tonic pupillary contraction) and hyporeflexia or areflexia (attenuated or extinguished muscle reflexes).
  • Systemic lupus erythematosus (SLE) – autoimmune disease with formation of autoantibodies mainly against antigens of the cell nuclei (so-called antinuclear antibodies = ANA), possibly also against blood cells and other body tissues.

Cardiovascular system (I00-I99)

  • Apoplexy* (stroke)
  • Heart failure* (cardiac insufficiency)
  • Unstable angina pectoris* (UA; engl. unstable angina) – one speaks of an unstable angina pectoris, if the complaints have increased in intensity or duration compared to the previous angina pectoris attacks.
  • Endocarditis* (inflammation of the inner lining of the heart).

Infectious and parasitic diseases (A00-B99).

  • Brucellosis* – generic term for diseases such as Bang’s disease or Malta fever, which is caused by the genus Brucella.
  • HIV infection* / AIDS*
  • Influenza (flu)
  • Malaria*
  • Mononucleosis infectiosa (infectious mononucleosis, glandular fever).
  • Osteomyelitis (bone marrow inflammation).
  • Tuberculosis* (consumption)

Musculoskeletal system and connective tissue (M00-M99)

Neoplasms – tumor diseases (C00-D48)

  • Carcinoid syndrome (synonym: carcinoid syndrome) – neuroendocrine tumors that cause discomfort due to increased production of neurotransmitters or peptide and steroid hormones (eg, histamine, kinins, serotonin). Symptoms: The first sign is often a persistent watery diarrhea (diarrhea). Typical for the carcinoids is the “flush symptomatology” (flush syndrome); this is a sudden blue-red discoloration of the face, neck and possibly the upper body to understand
  • Malignant neoplasms (malignant neoplasms) of all kinds; esp :
    • Myeloproliferative syndromes*
    • Lymphomas (typically with night sweats (with change of clothes!), performance kink and weight loss (B-symptomatic), and generalized lymph node swelling): lymphocytic leukemia (CLL), follicular B-non-Hodgkin lymphoma, highly malignant diffuse large B-non-Hodgkin lymphoma, Hodgkin’s disease.
  • Pheochromocytoma – predominantly benign tumors that occur mainly in the adrenal gland.

Psyche – nervous system (F00-F99; G00-G99).

  • Alcohol dependence
  • Nightmares
  • Anxiety disorders*
  • Apoplexy* * (stroke)
  • Depression*
  • Diabetic neuropathy* * (damage to peripheral nerves).
  • Drug withdrawal
  • Epilepsy
  • Gustatory sweating – form of sweating that occurs after eating.
  • Complex regional pain syndrome* * (Complex regional pain syndrome (CRPS); synonyms: Algoneurodystrophy, Sudeck’s disease, Sudeck’s dystrophy, Sudeck-Leriche syndrome, sympathetic reflex dystrophy (SRD)) – neurological-orthopedic clinical picture, which is based on an inflammatory reaction after injury to an extremity and in addition, the central pain processing is involved in the event; represents a symptomatology in which there are severe circulatory disturbances, edema (fluid retention) and functional restrictions after the intervention, as well as hypersensitivity to touch or pain stimuli; Occur in up to five percent of patients after distal radius fractures, but also after fractures or minor trauma to the lower extremity; early functional treatment (physical and occupational therapy), with medications for neuropathic pain (“nerve pain) and with topical (“local”) therapies lead to better long-term results.
  • Panic attacks*
  • Parkinson’s syndrome*
  • Peripheral neuropathies* /* * (disease of the external nerves).
  • Sleep apnea syndrome
  • Somatoform disorder – form of mental illness that results in physical symptoms without physical findings to be collected
  • Stress
  • Sympathetic nervous system damage – e.g., traumatic damage to the sympathetic nervous system or the sweat center in the hypothalamus; irritation of the sympathetic nervous system by a cervical rib; neck marker disease; paraplegic symptomatology.

Symptoms and abnormal clinical and laboratory findings not elsewhere classified (R00-R99).

  • Syncope (brief loss of consciousness).
  • Trauma* *

Medication

Operations

Further

* Major causes of secondary generalized hyperhidrosis* * Major causes of secondary regional and focal hyperhidrosis.