Irinotecan

Products Irinotecan is commercially available as an infusion concentrate (Campto, generic). It has been approved in many countries since 1998. In 2017, the nanoliposomal formulation irinotecan sucrosofate was released (Onivyde). Structure and properties Irinotecan (C33H38N4O6, Mr = 586.7 g/mol) is a semisynthetic derivative of camptothecin, a plant alkaloid derived from the tree. In the drug … Irinotecan

Pharmaceutical Active Ingredient

Definition Active ingredients are the active components of a drug that are responsible for its pharmacological effects. Drugs may contain a single active ingredient, multiple active ingredients, or complex mixtures such as herbal extracts. In addition to the active ingredients, a drug contains various excipients that should be as pharmacologically inert as possible. The percentage … Pharmaceutical Active Ingredient

Salvia Divinorum

Products belongs to narcotics and prohibited substances (Annex d) in many countries only since 2010 and may no longer be traded. The provisions of the Narcotics Act apply. Salvinorin A has not been included in the list so far. In numerous countries, jelly and corresponding preparations are available as legal hallucinogens and are sold, for … Salvia Divinorum

Pilocarpine Tablets

Products Pilocarpine has been commercially available in many countries since 2004 in the form of film-coated tablets (Salagen). See also under pilocaprine eye drops. Structure and properties Pilocarpine (C11H16N2O2, 208.26 g/mol) is present in the drops as pilocarpine hydrochloride, a white powder or colorless crystals that are very soluble in water. Pilocarpine is an alkaloid … Pilocarpine Tablets

Galantamine

Products Galantamine is commercially available in the form of sustained-release capsules (Reminyl, generic). It has been approved in many countries since 2000. Generics entered the market in 2014. Structure and properties Galantamine (C17H21NO3, Mr = 287.4 g/mol) is an alkaloid found in the Caucasian snowdrop, among other species, and is now produced synthetically. In pharmaceuticals, … Galantamine

Morphine: Drug Effects, Side Effects, Dosage and Uses

Products Morphine is available in many countries in various dosage forms, including tablets, capsules, oral suspension, syrup, morphine drops, suppositories, and injectables. It is also prepared in pharmacies as an extemporaneous formulation. Structure and properties Morphine (C17H19NO3, Mr = 285.3 g/mol) is present in drugs mainly as morphine hydrochloride and as morphine sulfate pentahydrate. These … Morphine: Drug Effects, Side Effects, Dosage and Uses

Α-PVP (Flakka)

Products α-Pyrrolidinopentiophenone (α-PVP) is trafficked as an illegal narcotic. It is also referred to as flakka. Structure and properties α-PVP (C15H21NO, Mr = 231.3 g/mol) is a synthetically prepared pyrrolidine derivative of cathinone that is related to MDPV. Cathinone is a natural alkaloid from the cathine shrub . α-PVP is closely related to pyrovalerone, an … Α-PVP (Flakka)