Cocci occur in several organizational forms and can lead to serious infections if they multiply rapidly and the infected person has a weakened immune system. Several cocci subspecies are so adaptable that they have now evolved strains that are resistant to conventional antibiotics. It is also particularly insidious that cocci can repeatedly cause severe food … Cocci: Infection, Transmission & Diseases
Products Zoledronic acid is commercially available as an infusion preparation (Zometa, Aclasta, generics). It has been approved in many countries since 2000. Structure and properties Zoledronic acid (C5H10N2O7P2, Mr = 272.1 g/mol) is present in drugs as zoledronic acid monohydrate, a white crystalline powder that is sparingly soluble in water. It is an imidazole derivative … Zoledronic Acid
Symptoms Classic cat scratch disease first manifests as a red papule or pustule at the site where the cat scratched or bit. Soon, local lymphadenitis (inflammation and swelling of the lymph nodes) occurs on the side of the body with the injury, often on the armpit or neck. Children and adolescents are particularly affected. Other … Cat Scratch Disease
Products Cefalexin is commercially available as a veterinary drug in the form of tablets, chewable tablets, and suspensions. It is available both as a monopreparation (e.g., Cefacat, Cefadog) and in combination with kanamycin (Ubrolexin). It has been approved in many countries since 1986. Structure and properties Cefalexin (C16H17N3O4S , Mr = 347.4 g/mol) exists as … Cefalexin
Products Netilmicin is no longer available in many countries. Netromycin is out of commerce. Effects Netilmicin (ATC J01GB07) is bactericidal. Indications Bacterial infectious diseases
Products Paromomycin is commercially available in the form of capsules (Humatin). It has been approved in many countries since 1961. Indications Precoma (clouding of consciousness preceding coma) and coma hepaticum (hepatic coma). Prophylaxis of hepatogenic encephalopathies. Reduction of intestinal flora before surgery Taeniasis (tapeworm) Intestinal amoebiasis
Products In many countries, only a few ear drops are currently on the market. They are also produced in pharmacies themselves. Structure and properties Ear drops are solutions, emulsions, or suspensions containing one or more active ingredients in liquids suitable for use in the ear canal. These include, for example, water, glycols, glycerol, propylene glycol, … Ear Drops
Vancomycin is the name given to a glycopeptide antibiotic. It is used when other antibiotics are no longer effective due to bacterial resistance. What is vancomycin? Vancomycin is the name given to a glycopeptide antibiotic. Vancomycin is a glycopeptide antibiotic used to treat Gram-positive bacteria. It has the status of a reserve antibiotic and is … Vancomycin: Effects, Uses & Risks
Elimination at the kidney The kidneys, along with the liver, play a central role in the elimination of pharmaceutical agents. They can be filtered at the glomerulus of the nephron, actively secreted at the proximal tubule, and reabsorbed at various tubular segments. In renal insufficiency, these processes are impaired. This may result in a renally … Dose Adjustment in Renal Insufficiency
Tobramycin is a well-known antibiotic that is particularly effective and is used for the therapy of infectious diseases. However, because of its aggressiveness, tobramycin is never the first-line agent. It is only used when milder agents no longer achieve acceptable results. What is tobramycin? The medical drug tobramycin is one of the antibiotics. It is … Tobramycin: Effects, Uses & Risks
Products Amikacin is commercially available as a solution for injection (Amikin). It has been approved in many countries since 1976. Structure and properties Amikacin (C22H43N5O13, Mr = 585.6 g/mol) is semisynthetically prepared from kanamycin A. It is found in drugs as amikacin sulfate, a white powder that is readily soluble in water. Effects Amikacin (ATC … Amikacin
Effects Aminoglycosides (ATC J01G) have bactericidal properties. They inhibit protein synthesis by bacteria by binding to subunits of ribosomes. Indications Bacterial infectious diseases Special indications (paromomycin) Active ingredients Amikacin Framycetin (= neomycin B) Gentamicin Neomycin Netilmicin Kanamycin (veterinary drug) Paromomycin Streptomycin Tobramycin, tobramycin inhalation, tobramycin eye drops. Aminoglycosides are not available perorally as polycations and … Aminoglycosides
