Symptoms Erectile dysfunction or so-called erectile dysfunction refers to the persistent or recurrent inability to achieve or maintain an erection, which is necessary for sexual activity. This makes sexual intercourse impossible and severely limits sexual life. For the affected man, erectile dysfunction can be a great psychological burden. It can trigger stress, negatively affect self-esteem … Erectile Dysfunction: Causes and Treatment
Products Abiraterone is commercially available in the form of film-coated tablets (Zytiga). It has been approved in many countries since 2011. Structure and properties Abiraterone acetate (C26H33NO2, Mr = 391.5 g/mol) exists as a white crystalline powder that is practically insoluble in water. It is a prodrug and is rapidly biotransformed in the body to … Abiraterone Acetate
Products There are no finished drug products containing stanozolol on the market in many countries. Structure and properties Stanozolol (C21H32N2O, Mr = 328.5 g/mol) is a steroid and a pyrazole derivative. It exists as a white, crystalline, and hygroscopic powder that is practically insoluble in water. Effects Stanozolol (ATC A14AA02) is anabolic. Indications for use … Stanozolol
Products Nafarelin is commercially available as a nasal spray (Synrelina). It has been approved in many countries since 1992. Structure and properties Nafarelin (C66H83N17O13, Mr = 1322.5 g/mol) is an agonist derivative and analog of gonadotropin-releasing hormone (GnRH). It is present in the drug as nafarelin acetate. It is a decapeptide that is administered nasally … Nafarelin
Products 5α-Reductase inhibitors are commercially available in many countries in the form of film-coated tablets and capsules. Finasteride was the first agent from this group to be approved in 1993 (USA: 1992). There are two finasteride drugs on the market. One with 5 mg for the treatment of prostate enlargement (Proscar, generic) and one with … 5Α-Reductase Inhibitors
Products Antiandrogens are mainly commercially available in the form of tablets, capsules, and injectables. Among the first steroidal agents was cyproterone acetate, which was patented in the 1960s. Flutamide was the first non-steroidal agent to be approved in the 1980s. Structure and properties A distinction is made between antiandrogens with a steroidal structure (like the … Antiandrogens
In the human body, numerous hormones ensure that vital processes take place. Among these are the sex hormones. While women have mainly estrogens and progestins, androgens are the sex hormones of men. The function of hormones can be limited by certain disorders. What are sex hormones? Sex hormones affect various mechanisms in the body. In … Sex Hormones: Function & Diseases
Products In many countries, no finished medicinal products containing alfatradiol are commercially available. In Germany, preparations for external use are available (e.g., Ell-Cranell). Structure and properties Alfatradiol (C18H24O2, Mr = 272.4 g/mol) or 17α-estradiol is a stereoisomer of the female sex hormone 17β-estradiol. Effects Alfatradiol inhibits the enzyme 5α-reductase, thereby inhibiting the synthesis of the … Alfatradiol
Androstenedione is a prohormone from which steroids such as estrone or testosterone are formed in the organism. “Andros” in Greek means “the man,” and the chemical structure is derived from the word suffix “dion.” Both word syllables refer to the fact that it is a sex hormone that has a masculinizing (i.e. androgenic) effect and … Androstenedione: Function & Diseases
PCO syndrome (polycystic ovary syndrome) is a disorder of female hormone balance. This disorder leads to an increase in male hormones, called androgens, which can result in infertility in addition to menstrual irregularities. PCO syndrome is also known as Stein-Leventhal syndrome. What is PCO syndrome? Polycystic ovary syndrome is one of the most common metabolic … Polycystic Ovary Syndrome: Causes, Symptoms & Treatment
Products Anastrozole is commercially available in the form of film-coated tablets (Arimidex, generic). It has been approved in many countries since 1996. Structure and properties Anastrozole (C17H19N5, Mr = 293.4 g/mol) exists as a white powder that is very sparingly soluble in water. It is a triazole derivative with a non-steroidal structure. Effects Anastrozole (ATC … Anastrozole
Products Androgens are commercially available as oral tablets and capsules, transdermal gels and transdermal patches, and injectables, among others. Testosterone was first isolated in the 1930s. Structure and properties Androgens generally have a steroidal structure and are related to testosterone. They are steroid hormones that are often present as esters in drugs. Effects Androgens (ATC … Androgens: Steroid Hormones
