Toxic Megacolon: Causes, Symptoms & Treatment

Toxic megacolon is a life-threatening complication of various bowel diseases. The colon becomes massively enlarged and septic-toxic inflammation occurs. What is toxic megacolon? Toxic megacolon is defined as acute dilatation of the colon with clinically prominent inflammation of the colon. Various diseases and, in particular, diseases of the colon may be considered as causes. However, … Toxic Megacolon: Causes, Symptoms & Treatment

Basiliximab: Effects, Uses & Risks

Basiliximab is a drug in the immunosuppressant drug class. It is used to prevent rejection after liver or kidney transplantation. What is basiliximab? Basiliximab is a drug in the immunosuppressant drug class. It is used to prevent rejection after liver or kidney transplantation. Basiliximab is a drug substance that belongs to the group of chimeric … Basiliximab: Effects, Uses & Risks

Doxorubicin: Effects, Uses & Risks

Doxorubicin is a drug belonging to the anthracycline group of substances, which are used in chemotherapy as cytostatics to treat various types of cancer. The active ingredient belongs to the intercalants. What is doxorubicin? Doxorubicin is a cytostatic drug. Cytostatic drugs are substances that inhibit cell division and/or cell growth. Therefore, they are mainly used … Doxorubicin: Effects, Uses & Risks

Cardiomegaly: Causes, Treatment & Help

Cardiomegaly, the pathological enlargement of the heart muscle, is a serious disease that usually occurs as a result of an underlying disease and must also be treated accordingly. There are a variety of diseases in the course of which cardiomegaly occurs. What is cardiomegaly? Cardiomegaly, the pathological enlargement of the heart muscle, is a serious … Cardiomegaly: Causes, Treatment & Help

Zidovudine (AZT)

Products Zidovudine is commercially available as film-coated tablets, capsules, and syrup (Retrovir AZT, combination products). It was approved in 1987 as the first AIDS drug. Structure and properties Zidovudine (C10H13N5O4, Mr = 267.2 g/mol) or 3-azido-3-deoxythymidine (AZT) is an analog of thymidine. It exists as an odorless, white to beige, crystalline substance that is soluble … Zidovudine (AZT)

Azacitidine

Products Azacitidine is commercially available as a lyophilizate for the preparation of a suspension for injection (Vidaza, generic). It has been approved in many countries since 2006. Structure and properties Azacitidine (C8H12N4O5, Mr = 244.2 g/mol) is a derivative of the nucleoside cytidine found in nucleic acids. It belongs to the pyrimidine nucleoside analogues. Azacitidine … Azacitidine

Rivaroxaban

Products Rivaroxaban is commercially available in the form of film-coated tablets (Xarelto, Xarelto vascular). It was approved in 2008 as the first agent in the direct factor Xa inhibitor group. Low-dose Xarelto vascular, 2.5 mg, was registered in many countries in 2019. Structure and properties Rivaroxaban (C19H18ClN3O5S, Mr = 435.9 g/mol) is a pure -enantiomer … Rivaroxaban

Favism: Causes, Symptoms & Treatment

Favism occurs due to a defect in the G6PD gene, which codes for an important enzyme in the human body. The enzyme deficiency leads to anemia and hemolysis and cannot be treated causally. The prognosis is very good if affected individuals avoid triggering substances for life. What is favism? Favism is the pathological course of … Favism: Causes, Symptoms & Treatment

Malnutrition: Causes, Symptoms & Treatment

Malnutrition, undernutrition or malnutrition is rather rare in the Western world, but malnutrition can still occur due to misunderstood diet or one-sided nutrition. Especially children and adolescents can suffer great damage in their mental and physical development due to malnutrition. This must be avoided through healthy and balanced nutrition. What is malnutrition? Malnutrition is a … Malnutrition: Causes, Symptoms & Treatment