Inhalation Anesthetics

Products Inhalation anesthetics are commercially available as volatile liquids or as gases for inhalation. Structure and properties Most inhalation anesthetics are halogenated ethers or hydrocarbons. Also used are inorganic compounds such as the gaseous nitrous oxide. The halogenated representatives exist as volatile liquids with a different boiling point. Because of their odor and irritant properties, … Inhalation Anesthetics

Polidocanol (Vein Sclerotherapy)

Products Polidocanol is commercially available as a solution for injection (Sclerovein, Aethoxysclerol). It has been approved in many countries since 1967. Synonyms for the active ingredient include polidocanol 600 and lauromacrogol 400. Structure and properties Polidocanol is a mixture of ethers of various macrogols with fatty alcohols, mainly lauryl alcohol (C12H26O). It exists as a … Polidocanol (Vein Sclerotherapy)

Elimination

Introduction Elimination is a pharmacokinetic process that describes the irreversible removal of active pharmaceutical ingredients from the body. It is composed of biotransformation (metabolism) and excretion (elimination). The most important organs for excretion are the kidney and the liver. However, drugs can also be excreted through the respiratory tract, hair, saliva, milk, tears, and sweat. … Elimination

Ketamine: Drug Effects, Side Effects, Dosage and Uses

Products Ketamine is commercially available as a solution for injection (Ketalar, generic). It has been approved in many countries since 1969. Esketamine nasal spray was approved in 2019 (Switzerland: 2020) for the treatment of treatment-resistant depression (see there). Structure and properties Ketamine (C13H16ClNO, Mr = 237.7 g/mol) is a cyclohexanone derivative derived from phencyclidine (“angel … Ketamine: Drug Effects, Side Effects, Dosage and Uses

Vancomycin: Effects, Uses & Risks

Vancomycin is the name given to a glycopeptide antibiotic. It is used when other antibiotics are no longer effective due to bacterial resistance. What is vancomycin? Vancomycin is the name given to a glycopeptide antibiotic. Vancomycin is a glycopeptide antibiotic used to treat Gram-positive bacteria. It has the status of a reserve antibiotic and is … Vancomycin: Effects, Uses & Risks

Allobarbital: Effects, Uses & Risks

Allobarbital is the name given to an active medical ingredient. It has a calming, soporific and pain-relieving effect. Throughout Europe, however, the drug is subject to numerous legal restrictions and thus also acquires the status of a drug. What is allobarbital? Allobarbital is thought to reduce brain activity as well as consciousness. As a result, … Allobarbital: Effects, Uses & Risks

Fear of Injections

Symptoms Shortly after an injection, some patients may experience the following symptoms: Pallor Malaise Dry mouth Cold sweat Low blood pressure Drowsiness, dizziness, confusion Nausea Fainting, syncope (short-lasting circulatory collapse). Convulsions (seizures) ECG changes Falls, accidents These disorders occur, for example, shortly after a vaccination, after parenteral administration of drugs, during acupuncture or blood sampling. … Fear of Injections

Anidulafungin

Products Anidulafungin is commercially available as a powder for the preparation of an infusion solution (Ecalta, generics). It has been approved in many countries since 2009. Structure and properties Anidulafungin (C58H73N7O17, Mr = 1140.3 g/mol) is a cyclic lipopeptide. It is a semisynthetic echinocandin obtained from a fermentation product of . It exists as a … Anidulafungin

Isoflurane

Products Isoflurane is commercially available as a pure liquid and has been approved in many countries since 1984 (Forene, generic). Structure and properties Isoflurane (C3H2ClF5O, Mr = 184.5 g/mol) exists as a clear, colorless, mobile, heavy, stable, and nonflammable liquid that is practically insoluble in water. It has a slightly pungent and ether-like odor. The … Isoflurane