Products Promazine is commercially available in the form of dragées (Prazine). It has been approved in many countries since 1957. Structure and properties Promazine (C17H20N2S, Mr = 284.4 g/mol) is present in drugs as promazine hydrochloride, a white crystalline powder that is very soluble in water. It is a dimethylamine derivative of phenothiazine and structurally … Promazine
Products Moxifloxacin is commercially available in the form of film-coated tablets, as an infusion solution, and eye drops (Avalox, Vigamox eye drops). It has been approved in many countries since 1999. Generic versions of the tablets went on sale in 2014. This article refers to oral administration; see also moxifloxacin eye drops. Structure and properties … Moxifloxacin
Products Hydrous alumina is commercially available in combination with magnesium hydroxide as a suspension and in the form of chewable tablets (Alucol). It has been approved in many countries since 1957. Structure and properties Alumina (Al2O3, Mr = 102.0 g/mol) is the oxide of aluminum. Hydrous alumina, as defined by the pharmacopoeia, contains 47 to … Alumina
Products Iron is available in the form of tablets, capsules, chewable tablets, drops, as a syrup, direct granules and as a solution for injection, among others (selection). These are approved drugs and dietary supplements. It is also combined with folic acid, with vitamin C and with other vitamins and minerals fix. Some dosage forms are … Iron
Background The iron content of an adult is about 3 to 4 g. In women, the value is somewhat lower than in men. About two-thirds is bound to heme as so-called functional iron, is present in hemoglobin, myoglobin, and in enzymes, and is essential for oxygen supply and metabolism. One-third is found in the iron … Iron Deficiency Causes and Treatment
Products Olmesartan is commercially available in the form of film-coated tablets (Olmetec, Votum, fixed combinations with amlodipine and hydrochlorothiazide). It has been approved in many countries since 2005. Generics were registered in 2016 and went on sale in 2017. Structure and properties Olmesartan is present in drugs as olmesartan medoxomil (C29H30N6O6, Mr = 558.6 g/mol), … Olmesartan
Most common mechanism of action Most drugs bind to a macromolecular target structure called a drug target. These are usually proteins such as receptors, transporters, channels, and enzymes, or nucleic acids. For example, opioids interact with endogenous opioid receptors to relieve pain. Targets can also be exogenous structures. Penicillins inhibit bacterial enzymes responsible for building … Mechanism of Action
Products Alendronate is commercially available in the form of weekly tablets (Fosamax, generic). It is also combined fixed with vitamin D (cholecalciferol) (Fosavance, generic) and has been approved in many countries since 1996. Structure and properties Sodium alendronate (C4H12NNaO7P2 – 3H2O, Mr = 325.1 g/mol) exists as a white crystalline powder that is soluble in … Alendronate
Products Gefitinib is commercially available in the form of film-coated tablets (Iressa). It was approved in many countries in 2011. Structure Gefitinib (C22H24ClFN4O3, Mr = 446.9 g/mol) is a morpholine and aniline quinazoline derivative. It exists as a white powder that is sparingly soluble in water, especially at high pH. Effects Gefitinib (ATC L01XE02) is … Gefitinib
Products In many countries, medicines containing carbaldrate are no longer on the market. Kompensan is no longer available. Effects Carbaldrate (ATC A02AB04) neutralizes stomach acid by reacting with hydrochloric acid to produce aluminum chloride and bicarbonate. Indications Treatment of gastric symptoms associated with hyperacidity such as heartburn, stomach pain, acid regurgitation, and bloating
Products Hydrotalcite was approved in many countries since 1992 and was commercially available as a suspension (Rennie Gel Hydrotalcite, off label). In Germany, it is also available as chewable tablets (Talcid, generic). Structure and properties Hydrotalcite (Al2Mg6(OH)16CO3 – 4H2O, Mr = 531.9 g/mol) is a magnesium aluminum hydroxide carbonate hydrate with a layered lattice structure. … Hydrotalcite
Products Capecitabine is commercially available in the form of film-coated tablets (Xeloda, generic). It has been approved in many countries since 1998. Structure and properties Capecitabine (C15H22FN3O6, Mr = 359.4 g/mol) is a prodrug and is converted to the cell-toxic 5-fluorouracil, the active drug, in a three-step process. Capecitabine exists as a white crystalline powder … Capecitabine
