Certolizumab

Products Certolizumab is commercially available as a solution for injection (Cimzia). It has been approved in many countries since 2007. Structure and properties Certolizumab is the Fab’ fragment of a recombinant humanized antibody. It is conjugated to polyethylene glycol (PEG) and is therefore also known as certolizumab pegol. Effects Certolizumab (ATC L04AB05) has selective immunosuppressive … Certolizumab

Invagination: Function, Role & Diseases

The term intussusception is used in medicine to refer to any type of invagination. This includes invagination of intestinal segments in infants and young children, phagocytosis in the immune response, or invagination of the blastocyst in embryogenesis. In embryogenesis, invagination represents the onset of gastrulation. What is intussusception? A very early stage of embryogenesis is … Invagination: Function, Role & Diseases

Blood cell sedimentation rate (BSG) | Heart muscle inflammation – Blood values

Blood cell sedimentation rate (BSG) The blood cell sedimentation rate (BSG for short) is measured within one and after two hours to determine by how much the blood cell components are reduced. The speed of this reduction is then determined. This is also an inflammation marker, which is increased when an inflammatory process is present … Blood cell sedimentation rate (BSG) | Heart muscle inflammation – Blood values

Exocytosis: Function, Role & Diseases

Exocytosis is the process of releasing substances from inside the cell to the outside. This complex process occurs in several steps. A distinction is made between constitutive exocytosis and stimulated exocytosis. What is exocytosis? Exocytosis is the process of releasing substances from inside the cell to the outside. Figure shows cell interior with components. The … Exocytosis: Function, Role & Diseases

Bacteriology: Treatment, Effects & Risks

The largest bacterium discovered to date was discovered in 1999. This is the sulfur pearl of Namibia, a species of bacteria that can even be seen with the naked eye. Its diameter is about three quarters of a millimeter. Bacteria are independent, microscopic living organisms that have a cellular structure and their own metabolism. The … Bacteriology: Treatment, Effects & Risks

Bevacizumab

Products Bevacizumab is commercially available as a concentrate for the preparation of an infusion solution (Avastin). It was approved in many countries and in the United States in 2004 and in the EU in 2005. Biosimilars have been approved in some countries and also in many countries. Structure and properties Bevacizumab is a recombinant, humanized … Bevacizumab

Aliskiren: Effects, Uses & Risks

Aliskiren is a drug that acts as a renin inhibitor (renin inhibitor) for the treatment of arterial hypertension. It is sold under various trade names as a monotherapy as well as a combination preparation and is available by prescription. The drug was approved in the United States in March 2007, in Switzerland in June, and … Aliskiren: Effects, Uses & Risks

Infection: Causes, Symptoms & Treatment

Infection refers to the body’s defense against invading microorganisms such as viruses, bacteria, or fungi. This results in infectious diseases with and without clinical symptoms. Infectious diseases range widely, from common childhood illnesses to serious infections that threaten life. What is an infection? An infection is caused by microorganisms attacking the body. The pathogens multiply … Infection: Causes, Symptoms & Treatment