Brivaracetam

Products Brivaracetam was approved in the EU, the United States, and many countries in 2016 in the form of film-coated tablets, oral solution, and solution for injection (Briviact). Structure and properties Brivaracetam (C11H20N2O2, Mr = 212.3 g/mol) is structurally and pharmacologically closely related to levetiracetam (Keppra, generics). Like levetiracetam, it is a pyrrolidinone derivative. Effects … Brivaracetam

Eszopiclone

Products Eszopiclone is commercially available in the United States in the form of film-coated tablets (Lunesta). The drug is not registered in many countries. In contrast, the racemate zopiclone (Imovane) is on the market. Structure and properties Eszopiclone (C17H17ClN6O3, Mr = 388.8 g/mol) is the -enantiomer of zopiclone. It belongs to the cyclopyrrolones. Eszopiclone exists … Eszopiclone

Clomethiazole

Products Clomethiazole is commercially available in capsule form and as a mixture (Distraneurin, UK: Heminevrin). It was developed at Roche in the 1930s. Structure and properties Clomethiazole (C6H8ClNS, Mr = 161.65 g/mol) is a chlorinated and methylated thiazole derivative. The compound is related to the thiazole moiety of vitamin B1 (thiamine). Effects Clomethiazole (ATC N05CM02) … Clomethiazole

Clonazepam

Products Clonazepam is commercially available as tablets, injectable solution, and oral drops (Rivotril). It has been approved in many countries since 1973. In the United States, it is marketed as Klonopin. Structure and properties Clonazepam (C15H10ClN3O3, Mr = 315.7 g/mol) exists as a faint yellowish crystalline powder that is practically insoluble in water. It is … Clonazepam

Clorazepate

Products Clorazepate is commercially available in the form of capsules and tablets (Tranxilium, generics). It has been approved in many countries since 1971. Structure and properties Clorazepate is present in drugs as dipotassium clorazepate (C16H11ClK2N2O4, Mr = 408.9 g/mol) is present, a white to pale yellow powder that is slightly to very slightly soluble in … Clorazepate

Temazepam

Products Temazepam is commercially available in capsule form (Normison). It has been approved in many countries since 1983. Structure and properties Temazepam (C16H13ClN2O2, Mr = 300.7 g/mol) is a white crystalline powder that is practically insoluble in water. It is present in drugs as a racemate (hydroxyl group). Temazepam belongs to the 5-aryl-1,4-benzodiazepines. Effects Temazepam … Temazepam

Lemon balm

Melissa officinalis Bee-weed, women’s well-being, lemon balmLemon balm grows up to 70 cm high. Square stem, strongly branched, small leaves and inconspicuous white flowers. When the fresh leaves are rubbed between the fingers, a lemon-like odor develops. Flowering time: July to August. Occurrence: Origins in the Mediterranean region, in our country also in gardens. Lemon … Lemon balm

Z-Drugs

Products Z-drugs – they are also called Z-substances – are usually taken in the form of film-coated tablets. In addition, other dosage forms such as sustained-release tablets and effervescent tablets are commercially available. Zolpidem (Stilnox) was the first substance from this group to be approved in many countries in 1990. In the literature, alluding to … Z-Drugs

Halazepam

Products Halazepam is commercially available in Portugal (Pacinone tablets) and elsewhere. The original trade name is paxipam. No drugs containing the active ingredient are currently registered in many countries, in Germany, or in the United States. Structure and properties Halazepam (C17H12ClF3N2O, Mr = 352.7 g/mol) is structurally closely related to diazepam (Valium). It exists as … Halazepam

Barbiturates

Products Barbiturates are commercially available in many countries in tablet and injectable forms. Few drugs are still available because barbiturates have become less important after the introduction of benzodiazepines and other psychotropic drugs. Barbiturates were most commonly used in the first half of the 20th century. Barbiturates were synthesized as early as the 19th century. … Barbiturates

Tizanidin

Products Tizanidine is commercially available in tablet and sustained-release capsule form (Sirdalud, Sirdalud MR, generics). It has been approved in many countries since 1983. Structure and properties Tizanidine (C9H8ClN5S, Mr = 253.7 g/mol) is present in drugs as tizanidine hydrochloride, a white crystalline powder that is somewhat soluble in water. It is an imidazoline and … Tizanidin

Nitrazepam

Products Nitrazepam is commercially available in tablet form (Mogadon). It has been approved in many countries since 1965. Structure and properties Nitrazepam (C15H11N3O3, Mr = 281.3 g/mol) is a nitrated 1,4-benzodiazepine. It exists as a yellow crystalline powder that is practically insoluble in water. Nitrazepam is structurally closely related to flunitrazepam (Rohypnol). Effects Nitrazepam (ATC … Nitrazepam