Products Preparations from garlic bulbs are commercially available in the form of dragées and capsules, among others. Garlic is also available in grocery stores, for example, fresh, dried and as a spice (granules, powder). It has been used as a remedy for thousands of years. Stem plant Garlic L. from the Amaryllis family (Amaryllidaceae) is … Garlic: Medicinal Uses
Products Calcium carbasalate (carbasalate calcium) is commercially available in the form of tablets and effervescent tablets (Alcacyl, Alca C with vitamin C). It has been approved in many countries since 1935. Note: Alcacyl powder contains lysine acetyl salicylate. Structure and properties Calcium carbasalate (C19H18CaN2O9, Mr = 458.4 g/mol) exists as a white crystalline powder that … Calcium Carbase Salad
Products Ginkgo extract is commercially available in the form of capsules, film-coated tablets, and as drops (e.g., Symfona, Tebokan, Tebofortin, Rezirkane), among others. In addition, dried ginkgo leaves are also available. It is recommended to use standardized and refined special extracts, as these contain the relevant ingredients and are free from undesirable substances, especially the … Ginkgo Health Benefits
Products Vorapaxar was approved in the form of film-coated tablets in the United States in 2014, in the EU in 2015, and in many countries in 2016 (Zontivity, MSD). Structure and properties Vorapaxar (C29H33FN2O4, Mr = 492.6 g/mol) is present as a white powder. It is a tricyclic 3-phenylpyridine derivative of himbacin, a natural alkaloid … Vorapaxar
Products Treprostinil is commercially available as an infusion solution (Remodulin, generic). It has been approved in many countries since 2004. Structure and properties Treprostinil (C23H34O5, Mr = 390.5 g/mol) is a synthetic prostacyclin. Effects Treprostinil (ATC B01AC21) has vasodilator and antiplatelet properties. Indications Primary pulmonary hypertension Pulmonary arterial hypertension
Products Epoprostenol is commercially available as a lyophilizate (Flolan, Veletri). It has been approved in many countries since 2000. Structure and properties Epoprostenol (C20H32O5, Mr = 352.5 g/mol) is a synthetic prostacyclin. Effects Epoprostenol (ATC B01AC09) has antiplatelet and vasodilatory properties. Indications Pulmonary hypertension
Products Cangrelor is commercially available as a powder for the preparation of an infusion solution (Kengrexal). It was approved in many countries in 2015. Structure and properties Cangrelor (C17H25Cl2F3N5O12P3S2, Mr = 776.4 g/mol) is an analog of adenosine triphosphate. Unlike other P2Y12 antagonists, it is not a prodrug. It is present in the drug as … Cangrelor
Products Proton pump inhibitors (PPIs) are commercially available in many countries in the form of film-coated tablets, MUPS tablets, capsules, as granules for preparation of an oral suspension, and as injectable and infusion preparations. The first active ingredient from this group to be approved in many countries was omeprazole (Antra, Losec), developed by Astra in … Proton Pump Inhibitors
Products Nonsteroidal anti-inflammatory drugs (NSAIDs) are available in numerous dosage forms. These include film-coated tablets, tablets, sustained-release tablets, oral suspensions, oral granules, suppositories, NSAID eye drops, lozenges, emulsifying gels, and creams (selection). The first active ingredient from this group was salicylic acid, which was used medicinally in the 19th century in the form of the … NSAID
Products Dabigatran is commercially available in capsule form (Pradaxa). It has been approved in many countries since 2012. It was first approved in 2008. Structure and properties Dabigatran (C25H25N7O3, Mr = 471.5 g/mol) is present in drugs as mesilate and in the form of the prodrug dabigatran etexilate, which is metabolized in the organism by … Dabigatran
Products Ticagrelor is commercially available in the form of film-coated tablets (Brilique). The active ingredient was approved in many countries in 2011. In 2018, additional meltable tablets were registered. Structure and properties Ticagrelor (C23H28F2N6O4S, Mr = 522.6 g/mol) is a cyclopentyltriazolopyrimidine without a thienopyridine structure. Ticagrelor is directly active. It has an active metabolite but, … Ticagrelor
Products Ticlopidine is out of commerce in many countries because of its adverse effects (thrombocytopenic purpura, blood count disorders). Ticlid film-coated tablets are no longer available. Structure and properties Ticlopidine (C14H14ClNS, Mr = 263.8 g/mol) is a thienopyridine that is structurally closely related to clopidogrel. Effects Ticlopidine (ATC B01AC05) is antiplatelet; see under P2Y12 antagonists. … Ticlopidine
