Quinisocaine

Products Quinisocaine was commercially available in many countries as an ointment (isoquinol) since 1973. In 2013, distribution was discontinued. Structure and properties Quinisocaine (C17H24N2O, Mr = 272.4 g/mol) is an isoquinoline derivative and is present in the drug as quinisocaine hydrochloride. It is classified as an amide-type local anesthetic. Effects Quinisocaine (ATC D04AB05) has local … Quinisocaine

Castellani Solution

Products Castellani solution is not commercially available as a registered finished drug in many countries and must be prepared in a pharmacy as an extemporaneous preparation. Retailers can also order it from specialized suppliers. The drug is named after Aldo Castellani (1877-1971), a well-known Italian tropical physician who developed it in the 1920s. Ingredients Traditional … Castellani Solution

Oclacitinib

Products Oclacitinib is commercially available in the form of film-coated tablets for dogs (Apoquel). It has been approved in many countries since 2014. Structure and properties Oclacitinib (C15H23N5O2S, Mr = 337.4 g/mol) is present in the drug as oclacitinib maleate. Effects Oclacitinib (ATCvet QD11AH90) has anti-inflammatory, antiallergic, and antipruritic properties. The effects are due to … Oclacitinib

Crotamiton

Products Crotamiton was available in many countries as a cream and lotion for external use (Eurax). It was approved in 1946. In 2012, its distribution was discontinued. Structure and properties Crotamiton (C13H17NO, Mr = 203.3 g/mol) exists as a colorless to pale yellow, oily liquid with a slight amine odor. It is sparingly soluble in … Crotamiton

Bern Wart Ointment

Products Bern Wart Ointment is not commercially available as a finished drug product and must be prepared as a magistral prescription or house specialty in a pharmacy. Ingredients The ointment contains 2-naphthol, resorcinol, salicylic acid, thymol, and phenol in petrolatum and kerosene. A manufacturing specification can be found in the DMS. Bern wart ointments with … Bern Wart Ointment

Ear Drops

Products In many countries, only a few ear drops are currently on the market. They are also produced in pharmacies themselves. Structure and properties Ear drops are solutions, emulsions, or suspensions containing one or more active ingredients in liquids suitable for use in the ear canal. These include, for example, water, glycols, glycerol, propylene glycol, … Ear Drops

Lokivetmab

Products Lokivetmab was approved in the EU in 2017 and in many countries in 2018 in the form of a solution for injection (Cytopoint, Zoetis Belgium SA). Lokivetmab was the first monoclonal antibody to be cleared for animals. In the United States, locivetmab was approved in 2015 (Canine Atopic Dermatitis Immunotherapeutic). Structure and properties Lokivetmab … Lokivetmab

Prednicarbate

Products Prednicarbate is commercially available as a cream, solution, and ointment (Prednitop, Prednicutan). It has been approved in many countries since 1990. Structure and properties Prednicarbate (C27H36O8, Mr = 488.6 g/mol) belongs to the class of potent glucocorticoids (class III). It is a non-halogenated prednisolone derivative. It exists as an odorless, white to yellowish-white, crystalline … Prednicarbate

Capsaicin Cream

Products Capsaicin cream at 0.025% or 0.075% (also 0.1%) is not registered as a finished drug in many countries, unlike other countries. It is produced as an extemporaneous preparation in pharmacies. The specialized trade can also order them from specialized service providers. On the other hand, patches containing the active ingredient (Qutenza) are approved as … Capsaicin Cream

Dimetindenmaleate

Products Dimetinden maleate is commercially available as drops, gel, lotion, nasal spray, and nasal drops (Fenistil, Feniallerg, Vibrocil, Otriduo). The nasal products also contain the vasoconstrictor phenylephrine. The Fenistil products used internally (systemically) were renamed Feniallerg in 2009. The capsules and dragées are no longer available. Structure and properties Dimetind (C20H24N2, Mr = 292.4 g/mol) … Dimetindenmaleate