Products Pemetrexed is commercially available as an infusion drug (Alimta, generic). It has been approved in many countries since 2005. Structure and properties Pemetrexed (C20H21N5O6, Mr = 427.4 g/mol) is a folic acid analog. It is present in drugs hydrated and as a disodium salt, in the original preparation as pemetrexed disodium heptahydrate, a white … Pemetrexed
Products Cabozantinib is commercially available in the form of film-coated tablets (Cabometyx). It was approved in the United States in 2012, in the EU in 2013, and in many countries in 2017. In some countries, Cometriq capsules are additionally on the market for the treatment of medullary thyroid carcinoma. This article relates to renal cell … Cabozantinib
Products Metformin is commercially available in many countries in the form of film-coated tablets and has been available since 1960. In addition to the original Glucophage, numerous generics are available today. Metformin is often combined with various other antidiabetic drugs fix. It has been used medically since 1957. Other antidiabetic biguanides such as phenformin and … Metformin: Drug Effects, Side Effects, Dosage and Uses
Products Trabectedin is commercially available as a powder for the preparation of an infusion solution concentrate (Yondelis). It has been approved in many countries since 2009. Structure and properties Trabectedin (C39H43N3O11S, Mr = 761.8 g/mol) is a tetrahydroisoquinoline alkaloid from sea squirt , a marine animal belonging to the tunicates. The active ingredient is produced … Trabectedin
Products Lenvatinib was approved in many countries in 2015 in capsule form (Lenvima). In 2017, Kisplyx capsules were also approved. Structure and properties Lenvatinib (C21H19ClN4O4, Mr = 426.9 g/mol) is present in the drug as lenvatinib mesilate, a white to pale reddish-yellow powder that is sparingly soluble in water. It is a quinoline and carboxamide … Lenvatinib
Products Hepatitis A vaccine is commercially available as an injection suspension (Havrix). It has been licensed in many countries since 1993. A fixed combination with hepatitis B vaccine is also available (Twinrix). Structure and properties Hepatitis A vaccine is either hepatitis A virus inactivated with formaldehyde or a liposomal preparation of hepatitis A virus antigen. … Hepatitis A Vaccine
Products Temozolomide is commercially available as capsules and as a powder for the preparation of an infusion solution (Temodal, generics). It has been approved in many countries since 1999. Structure and properties Temozolomide (C6H6N6O2, Mr = 194.2 g/mol) is an imidazotetrazine derivative. It is a prodrug that is biotransformed by hydrolysis to the active metabolite … Temozolomide
Products Propranolol is approved for the treatment of hemangioma in the form of an oral solution (hemangiol). The drug goes on sale in many countries in November 2014. Structure and properties Propranolol (C16H21NO2, 259.34 g/mol) is present in drugs as propranolol hydrochloride, a white powder that is soluble in water. It is a racemate. Effects … Propranolol (Hemangioma)
Products Ivermectin is commercially available in some countries in tablet form (Stromectol). It has not yet been registered in many countries and therefore must be imported from abroad if needed. Ivermectin has been used medicinally since the 1980s, initially primarily as a veterinary drug. This article refers to peroral administration in humans. See also under … Ivermectin
Symptoms Postpartum depression is a mental illness that begins in women within the first few months after delivery. Depending on the source, onset is reported within 1 to 12 months after delivery. It manifests itself in the same symptoms as other depressions and lasts several weeks to months. Postpartum depression is common and affects between … Postnatal Depression: Causes and Treatment
Products Adderall is commercially available in the United States in the form of tablets and sustained-release capsules (Adderall, Adderall XR). It is not registered in many countries, but related products are available. The name is derived from the abbreviation ADD (attention deficit disorder, ADHD). Structure and properties Adderall contains a mixture of the following four … Adderall
Products Docetaxel is commercially available as an infusion preparation (Taxotere, generics). It was approved in many countries in 1996 as a second taxane after paclitaxel (Taxol). Structure and properties Docetaxel (C43H53NO14, Mr = 807.9 g/mol) is present in the drug as docetaxel trihydrate, a white powder that is practically insoluble in water. The lipophilic drug … Docetaxel
