Amfepramone: Effects, Uses & Risks

Amfepramone is an indirect alpha-sympathomimetic and is used in Germany as an appetite suppressant. Because of a not inconsiderable potential for abuse, the active ingredient is prescribed only in urgent cases for a short time for the supportive treatment of obesity. What is amfepramone? Because of a not insignificant potential for abuse, the drug is … Amfepramone: Effects, Uses & Risks

Kath

Products The leaves of the cath bush and the active ingredient cathinone are among the prohibited narcotics in many countries (Appendix d). The weaker-acting cathine, however, is not prohibited. In some countries, however, cath is legal. Stem plant Cath shrub, from the spindle tree family (Celastraceae), is an evergreen plant. It was first described scientifically … Kath

Amphetamine

Products In many countries, no drugs containing amphetamine are currently registered. The active ingredient is subject to narcotics legislation and requires an aggravated prescription, but is basically not prohibited like other substances from the amphetamine group. In some countries, medicines containing dexamphetamine are on the market, for example in Germany and the USA. Structure and … Amphetamine

Benfluorex

Products Benfluorex was marketed in many countries as Mediaxal (150 mg, Servier) until 1998. Today, it is no longer on the market. In France and other European countries, it was available as Mediator, among other products. Its approval was not withdrawn in France until 2009, although the risk for cardiotoxic side effects of comparable drugs … Benfluorex

Cathin

Products In many countries, there are currently no registered medicines containing the active ingredient Cathin. Products containing Cathine are not banned, but are subject to prescription and narcotics laws. Structure D-cathine (C9H13NO, Mr = 151.2 g/mol) is a natural substance from the cath (, Celastraceae), which is also produced synthetically. It is a hydroxylated amphetamine … Cathin

Cathinon

Products Cathinone is not approved as a drug in many countries and is therefore not commercially available. It is one of the banned narcotics (d). In recent years, there have been increasing reports of synthetic cathinone derivatives (designer drugs) such as mephedrone and MDPV, which were initially sold legally as fertilizer and bath salts. Legislation … Cathinon

Sibutramine

Products and withdrawal from the market Sibutramine was approved in 1999 and was commercially available in many countries in 10- and 15-mg capsule form (Reductil, Abbott AG). On March 29, 2010, Abbott AG, in consultation with Swissmedic, informed the public that the marketing authorization had been suspended. Since then, sibutramine may no longer be prescribed … Sibutramine

Ketanserin: Effects, Uses & Risks

Ketanserin refers to a substance that has wound-healing and blood pressure-lowering properties. The active ingredient is a serotonin antagonist and acts on different receptors in the human brain. However, ketanserin does not have approval as a drug for these purposes in the Federal Republic and is only used clinically in exceptional cases. What is ketanserin? … Ketanserin: Effects, Uses & Risks

Cannabidiol

Products In many countries, there are currently no medicines approved that contain only cannabidiol. However, the active ingredient is a component of the cannabis oral spray Sativex, which is registered as a drug for MS treatment in many countries and also contains THC. The oral solution Epidiolex or Epidyolex was approved as a drug in … Cannabidiol

Cannabinoid Receptor Antagonists

Products Cannabinoid receptor antagonists are no longer on the market in many countries. Rimonabant (Acomplia) was withdrawn from the market in 2008 because it can cause psychiatric disorders, particularly depression. Effects Cannabinoid receptor antagonists have appetite suppressant, lipid-lowering, antidiabetic, analgesic (antiallodynic, antinociceptive), and anti-inflammatory properties. The effects of cannabinoid receptor antagonists are largely opposite to … Cannabinoid Receptor Antagonists

Amfepramone

Products Amfepramone is commercially available in the form of capsules (e.g., Regenon). The drug is not registered in many countries. Structure and properties Amfepramone (C 13 H 19 NO, M r = 205.3 g/mol) is structurally related to cathinone. Effects Amfepramone (ATC A08AA03) has indirect sympathomimetic, appetite suppressant, and antiadipose properties. The effects are due … Amfepramone

Alginic Acid: Effect, Uses & Risks

Alginic acid has many uses in medical applications. On the one hand, it is considered a thickening agent and as such can restructure liquid medicines into a gel. On the other hand, it is used therapeutically for indigestion and heartburn, and as an appetite suppressant. What is alginic acid? Alginic acid is used therapeutically for … Alginic Acid: Effect, Uses & Risks