Chewing Gums

Products Chewing gums with active pharmaceutical ingredients are available in pharmacies and drugstores. In many countries, only a few pharmaceuticals are approved as chewing gums. Most belong to other product categories, for example, confectionery, dietary supplements, or dental care products. Structure and properties Active ingredient-containing chewing gums are solid single-dose preparations with a base mass … Chewing Gums

Sweeteners: the Calorie-Free Alternative

The preference for sweet is innate to us humans and we do not like to give up this taste experience. However, fruit cakes, desserts, etc. have the major disadvantage that they are very high in calories. The sweeteners that can be used as alternative sweeteners are: Acesulfame, aspartame, cyclamate, neohesperidin DC, saccharin and thaumatin. Advantages … Sweeteners: the Calorie-Free Alternative

Auxiliary Materials

Definition On the one hand, drugs contain the active ingredients that mediate the pharmacological effects. On the other hand, they consist of excipients, which are used for the production or to support and regulate the drug effect. Placebos, which consist only of excipients and contain no active ingredients, are an exception. Excipients can be of … Auxiliary Materials

Aspartame

Products Aspartame is found in numerous products. It is available as a pure substance in specialized stores. Aspartame was accidentally discovered by James M. Schlatter at Searle in 1965. Structure and properties Aspartame (C14H18N2O5, Mr = 294.3 g/mol) exists as a white, crystalline, odorless, and slightly hygroscopic powder that is sparingly soluble in water (10 … Aspartame

Neotame

Products Neotame is available from specialty retailers as a pure powder. Structure and properties Neotame (C20H30N2O5, Mr = 378.5 g/mol) is structurally related to aspartame, from which it is synthesized. It exists as a white powder and is soluble in water. Effects Neotame has a sweet taste and is used as a sweetener. It is … Neotame

Acesulfame K

Products Acesulfame K is found as an additive in numerous products. It is available as a pure substance in specialty stores. The sweetener was discovered by chance in 1967 by Karl Clauß at Hoechst AG. Structure and properties Acesulfame K (C4H4KNO4S, Mr = 201.2 g/mol) stands for acesulfame potassium, the potassium salt of acesulfame. It … Acesulfame K

Saccharin

Products Saccharin is commercially available in the form of small tablets, drops, and powder (e.g., Assugrin, Hermestas), among others. It was accidentally discovered in 1879 by Constantin Fahlberg at Johns Hopkins University in Baltimore. Structure and properties Saccharin (C7H5NO3S, Mr = 183.2 g/mol) is usually present as saccharin sodium, a white crystalline powder or colorless … Saccharin

Aspartame: Sweet Poison?

It’s in sugar-free chewing gum, low-calorie yogurts and numerous other diet products. Aspartame is a chemical sweetener that promises low-sugar diets, but its side effects are controversial. While critics accuse aspartame of carcinogenic ingredients, experts give the all-clear – despite side effects that need to be considered. Aspartame: discovery and approval Back in 1965, aspartame … Aspartame: Sweet Poison?