Beta-Lactamase Inhibitors
Active ingredients Avibactam Clavulanic acid Sulbactam Tazobactam Vaborbactam
avibactam
Ceftazidime
Products Ceftazidime is commercially available as a solution for injection and infusion (Fortam, generic). It has been approved in many countries since 1984. In 2019, a fixed-dose combination with the beta-lactamase inhibitor avibactam was registered; see Avibactam (Zavicefta). Structure and properties Ceftazidime (C22H22N6O7S2 – 5 H2O, Mr = 637 g/mol) is a white crystalline powder … Ceftazidime
Avibactam
Products Avibactam was approved in the United States in 2015, in the EU in 2016, and in many countries in 2019 in fixed combination with the cephalosporin ceftazidime as a powder for a concentrate for solution for infusion (Zavicefta). Structure and properties Avibactam (C7H11N3O6S, Mr = 265.25 g/mol), unlike other beta-lactamase inhibitors, is not itself … Avibactam
