biguanide

Diabetes Mellitus Type 2: Causes and Treatment

Symptoms The possible acute symptoms of type 2 diabetes include: Thirst (polydipsia) and hunger (polyphagia). Increased urination (polyuria). Visual disturbances Weight loss Fatigue, exhaustion, declining performance. Poor wound healing, infectious diseases. Skin lesions, itching Acute complications: Hyperacidity (ketoacidosis), hyperosmolar hyperglycemic syndrome. Untreated diabetes is far from harmless and can lead in the longer term to … Diabetes Mellitus Type 2: Causes and Treatment

Polihexanide

Products Polihexanide is commercially available as a solution and concentrate (Lavasept). It has been approved in many countries since 1991. Structure and properties Polihexanide (C8H19N5, Mr = 185.3 g/mol) is a biguanide derivative. Effects Polihexanide (ATC D08AC05) has bactericidal and fungicidal properties. Indications For antiseptic wound treatment and prophylaxis of bone and soft tissue infections. … Polihexanide

Phenformin

Products Phenformin has been off the market in many countries since the late 1970s because of the potential adverse effects. Structure and properties Phenformin (C10H15N5, Mr = 205.3 g/mol) is a biguanide with a similar structure to metformin. Phenformin was the first agent in this group of drugs. Effects Phenformin (ATC A10BA01) has antidiabetic and … Phenformin

Metformin

Synonyms in a broader sense Diabetes drugs, drugs Diabetes mellitus, Biguanide, Glucophage®, Mescorit®, Diabesin®, Siofor® How do biguanides act like metformin? According to current medical guidelines, metformin is used first when diabetes mellitus cannot be controlled well through exercise, sport and weight loss. Metformin has been on the market for decades and has proven to … Metformin

When should you not take Metformin? | Metformin

When should you not take Metformin? Just to avoid the undesirable effects under a metformin intake, the following contraindications should be noted. If your kidneys are not working properly, metformin should not be taken. Especially diabetics often have limited kidney function. Your doctor will check your blood for a certain kidney value (creatinine) and thus … When should you not take Metformin? | Metformin

Metformin and alcohol | Metformin

Metformin and alcohol If you are taking metformin, the excessive consumption of alcohol carries a number of dangers that should be taken seriously. One particularly important point is that you will be alcoholized much faster than without taking the drug. It is very easy to overlook the point when it is enough with the alcohol … Metformin and alcohol | Metformin

Proguanil

Products Proguanil is commercially available in the form of film-coated tablets and exclusively as a fixed combination with atovaquone (Malarone, generic). It has been approved in many countries since 1997. Generics went on sale in 2013. Structure and properties Proguanil (C11H16ClN5, Mr = 253.7 g/mol) is an active ingredient of the biguanide group. It exists … Proguanil

Buformin

Products Buformin (Silubin retard, dragées) is no longer commercially available in many countries and many more because of the potential adverse effects. Structure and properties Buformin (C6H15N5, Mr = 157.2 g/mol) is a 1-butylbiguanide with a similar structure to metformin from the same drug group. It is present in drugs as buformin hydrochloride. Effects Buformin … Buformin