Products Temazepam is commercially available in capsule form (Normison). It has been approved in many countries since 1983. Structure and properties Temazepam (C16H13ClN2O2, Mr = 300.7 g/mol) is a white crystalline powder that is practically insoluble in water. It is present in drugs as a racemate (hydroxyl group). Temazepam belongs to the 5-aryl-1,4-benzodiazepines. Effects Temazepam … Temazepam
Products Z-drugs – they are also called Z-substances – are usually taken in the form of film-coated tablets. In addition, other dosage forms such as sustained-release tablets and effervescent tablets are commercially available. Zolpidem (Stilnox) was the first substance from this group to be approved in many countries in 1990. In the literature, alluding to … Z-Drugs
Products Zaleplon was commercially available in capsule form (Sonata, 5 mg, 10 mg). It was approved in many countries in 1999. It was discontinued from distribution in April 2013. Structure and properties Zaleplon (C17H15N5O, Mr = 305.3 g/mol) is a pyrazolopyrimidine and exists as a white powder that is practically insoluble in water. It is … Zaleplon
Products Droperidol is commercially available as a solution for injection (Droperidol Sintetica). It has been approved in many countries since 2006. Structure and properties Droperidol (C22H22FN3O2, Mr = 379.4 g/mol) structurally belongs to the butyrphenones and exists as a white powder that is practically insoluble in water. It is a benzimidazolinone derivative. Effects Droperidol (ATC … Droperidol
Products Nicomorphine was commercially available in the form of tablets, suppositories, and as a solution for injection (Vilan). It had been approved in many countries since 1957. It was discontinued in 2015. Structure and properties Nicomorphine (C29H25N3O5, Mr = 495.5 g/mol), like heroin, is an ester as well as a nicotinic acid derivative of morphine … Nicomorphine
Products Esketamine nasal spray was approved in the US and EU in 2019 and in many countries in 2020 (Spravato). Structure and properties –Ketamine is the pure -enantiomer of ketamine (C13H16ClNO, Mr = 237.7 g/mol). The racemate ketamine is a cyclohexanone derivative derived from phencyclidine (“angel dust”). It is a ketone and an amine and … Esketamine Nasal Spray
Products Nitrazepam is commercially available in tablet form (Mogadon). It has been approved in many countries since 1965. Structure and properties Nitrazepam (C15H11N3O3, Mr = 281.3 g/mol) is a nitrated 1,4-benzodiazepine. It exists as a yellow crystalline powder that is practically insoluble in water. Nitrazepam is structurally closely related to flunitrazepam (Rohypnol). Effects Nitrazepam (ATC … Nitrazepam
Products Psychotropic drugs are commercially available, for example, in the form of tablets, melting tablets, dragées, capsules, drops, solutions and as injectables. The first psychotropic drugs were developed in the 1950s. Structure and properties Psychotropic drugs vary chemically, but groups with a common structure can be identified, for example, the benzodiazepines, the phenothiazines, and the … Psychotropic Drugs: Types, Effects, Indications, Dosage
Products Triazolam is commercially available in tablet form (Halcion). It has been approved in many countries since 1978. Structure and properties Triazolam (C17H12Cl2N4, Mr = 343.2 g/mol) exists as a white crystalline powder that is poorly soluble in water. It is a triazole derivative (triazol-am). Effects Triazolam (ATC N05CD05) has sedative, antianxiety, anticonvulsant, amnesic, and … Triazolam
Products Fentanyl is commercially available in many countries in the form of lozenges, buccal tablets, sublingual tablets, as a fentanyl patch (e.g., Durogesic, generic), and as a solution for injection. It is a narcotic and is subject to enhanced prescription requirements. Structure and properties Fentanyl (C22H28N2O, Mr = 336.5 g/mol) exists as a white powder … Fentanyl: Drug Effects, Side Effects, Dosage and Uses
Products Scopolamine is currently sold in many countries exclusively in the form of eye drops. The transdermal patch Scopoderm TTS and other medications are no longer available. In some countries, other medicines containing scopolamine are available, such as Kwells motion sickness tablets and the Transderm Scop transdermal patch. This article refers to peroral use. In … Scopolamine
Products Rotigotine is commercially available as a transdermal patch in various potencies (Neupro). It was approved in many countries in 2006 as the first TTS for Parkinson’s disease therapy. Structure and properties Rotigotine (C19H25NOS, Mr = 315.5 g/mol) is an aminotetralin and thiophene derivative structurally related to dopamine. It has a non-ergoline structure and exists … Rotigotine