Pregabalin

Products Pregabalin is commercially available in capsule form and as an oral solution (Lyrica, generics). It was approved in the United States and EU in 2004 and in many countries in 2005. Structure and properties Pregabalin (C8H17NO2, Mr = 159.2 g/mol) exists as a white crystalline powder that is soluble in water. It was developed … Pregabalin

Alfentanil

Products Alfentanil is commercially available as a solution for injection (Rapifen). It has been approved in many countries since 1983. Structure and properties Alfentanil (C21H32N6O3, Mr = 416.5 g/mol) is a 4-anilidopiperidine and a tetrazole derivative. It is present in the drug as alfentanil hydrochloride, a white powder that is readily soluble in water. The … Alfentanil

Nortriptyline

Products Nortriptyline was commercially available in the form of film-coated tablets (nortrilen). It was approved in many countries in 1964. It was discontinued from distribution in 2016. Structure and properties Nortriptyline (C19H21N, Mr = 263.4 g/mol) is present in drugs as nortriptyline hydrochloride, a white powder that is sparingly soluble in water. It is an … Nortriptyline

Clonidine: Drug Effects, Side Effects, Dosage and Uses

Products Clonidine is commercially available in many countries as tablets and as a solution for injection and has been approved since 1970 (Catapresan). In some countries, clonidine is approved for the treatment of ADHD (eg, Kapvay sustained-release tablets). This article refers to its use in ADHD. Structure and Properties Clonidine (C9H9Cl2N3, Mr = 230.1 g/mol) … Clonidine: Drug Effects, Side Effects, Dosage and Uses

Methoprene

Products Methoprene is available in many countries exclusively in combination with the insecticide fipronil as a spot-on solution (Frontline Combo). Structure and properties Methoprene (C19H34O3, Mr = 310.5 g/mol) is present in drugs in the form of the active -enantiomer S-methoprene. Effects Methoprene (ATCvet QP53AX65) is ovicidal and larvicidal. It inhibits the development of immature … Methoprene

Ciclosporin Eye Drops

Products Ciclosporin eye drops were approved in the EU in 2015 and in many countries in 2016 (Ikervis). They have been registered in the United States since 2009 (Restasis). Structure and properties Ciclosporin (C62H111N11O12, Mr = 1203 g/mol) exists as a white powder that is practically insoluble in water. It is extracted from the mushroom … Ciclosporin Eye Drops

Halofuginone

Products Halofuginone is commercially available as an oral solution as a veterinary drug. It has been approved in many countries since 2003. Structure and properties Halofuginone (C16H17BrClN3O3, Mr = 414.7 g/mol) is a quinazoline derivative. Effects Halofuginone (ATCvet QP51AX08) has antiprotozoal properties against . Indications For the treatment of diarrhea caused by (cryptosporidiosis) in newborn … Halofuginone

Nitenpyram

Products Nitenpyram is commercially available in tablet form (Capstar). It has been approved in many countries since 1999. Structure and properties Nitenpyram (C11H15ClN4O2, Mr = 270.7 g/mol) is a chlorinated pyridine derivative derived from nicotine. It is structurally related to imidacloprid. Effects Nitenpyram (ATCvet QP53BX02) has insecticidal properties. The effects are due to binding to … Nitenpyram

Alprostadil

Products Alprostadil is commercially available as an injectable, urethral rod, and infusion concentrate (Caverject, Muse, Prostin VR). It has been approved in many countries since 1983. An alprostadil cream is also approved in some countries. Structure and properties Alprostadil (C20H34O5, Mr = 354.5 g/mol) is a white to slightly yellowish crystalline powder that is practically … Alprostadil

Almotriptan for Migraine Headache

Products Almotriptan is commercially available in the form of film-coated tablets (Almogran). It has been approved in many countries since 2004. Structure and properties Almotriptan (C17H25N3O2S, Mr = 335.5 g/mol) is present in drugs as almotriptan-D,L-hydrogenmalate, a white to slightly yellowish crystalline powder that is soluble in water. Effects Almotriptan (ATC N02CC05) has vasoconstrictive, analgesic, … Almotriptan for Migraine Headache

Fluoxetine: Drug Effects, Side Effects, Dosage and Uses

Products Fluoxetine is commercially available as tablets, dispersible tablets, and capsules (Fluctine, generics, USA: Prozac). It has been approved in many countries since 1991. Structure and properties Fluoxetine (C17H18F3NO, Mr = 309.3 g/mol) is present in the drugs as fluoxetine hydrochloride, a white crystalline powder that is sparingly soluble in water. It is a racemate … Fluoxetine: Drug Effects, Side Effects, Dosage and Uses

Heat Patch

Products Various heat patches and heat wraps are on the market in many countries. Some products are registered as medicines, while others are marketed as medical devices. Ingredients Some heat patches contain a capsicum extract obtained from the dried, ripe fruits of -species (cayenne pepper, “hot chili”). The extract’s ingredients include capsaicinoids such as capsaicin. … Heat Patch