Atorvastatin

Products Atorvastatin is commercially available in the form of film-coated tablets (Sortis, generic, auto-generic). It has been approved in many countries since 1997. Atorvastatin is also available as a fixed combination with ezetimibe; see Atorvastatin and Ezetimibe. Structure and Properties Atorvastatin (C33H35FN2O5, Mr = 558.64 g/mol) is present in drugs as atorvastatin calcium trihydrate, (atorvastatin)2– … Atorvastatin

Levofloxacin

Products Levofloxacin is commercially available as film-coated tablets and as an infusion solution (Tavanic, generic). It was approved in many countries in 1998. Generics came on the market in 2011. In 2018, a solution for a nebulizer was registered (Quinsair). The racemate ofloxacin is available as tablets (Tarivid), eye drops, and eye ointment (Floxal). Structure … Levofloxacin

Repaglinide: Effects, Uses & Risks

Repaglinide is an active substance, which is used in the disease diabetes mellitus type 2, when dietary measures, weight reduction and physical training do not sufficiently reduce blood sugar. By inhibiting the potassium channels of the beta cells in the pancreas, the drug leads to the release of insulin. If the dosage and intake conditions … Repaglinide: Effects, Uses & Risks

Simvastatin: Drug Effects, Side Effects, Dosage and Uses

Products Simvastatin is commercially available in the form of film-coated tablets (Zocor, generics). It is also combined fixed with ezetimibe (Inegy, generic). Simvastatin has been approved in many countries since 1990. Structure and properties Simvastatin (C25H38O5, Mr = 418.6 g/mol) exists as a white crystalline powder that is practically insoluble in water. It is a … Simvastatin: Drug Effects, Side Effects, Dosage and Uses

Mycophenolate

Products Mycophenolate is commercially available in the form of enteric-coated film-coated tablets (Myfortic). It has been approved in many countries since 2002. Structure and properties Mycophenolate is the deprotonated form of mycophenolic acid (C17H20O6, Mr = 320.3 g/mol). It is present in the drug as mycophenolate sodium, a white crystalline powder that is highly soluble … Mycophenolate

Mycophenolate Mofetil

Products Mycophenolate mofetil is commercially available in the form of film-coated tablets, capsules, as an injectable, and as a suspension (CellCept, generics). It has been approved in many countries since 1995. Structure and properties Mycophenolate mofetil (C23H31NO7, Mr = 433.5 g/mol) exists as a white crystalline powder and is practically insoluble in water. It is … Mycophenolate Mofetil

Alopecia Areata

Symptoms Alopecia areata manifests as single or multiple, clearly defined, smooth, oval to round hairless areas. The skin is healthy and not inflamed. Hair loss most commonly occurs on the hair of the head, but all other body hair, such as the eyelashes, eyebrows, underarm hair, beard, and pubic hair, may be affected, and changes … Alopecia Areata

Naproxen: Drug Effects, Side Effects, Dosage and Uses

Products Naproxen has been approved in many countries since 1975 and is commercially available in the form of film-coated tablets (e.g., Apranax, Proxen, generics). Other dosage forms such as the suppositories and the juice are no longer available. Drugs with a deep dose have been available over the counter since 1999 (Aleve with 200 mg … Naproxen: Drug Effects, Side Effects, Dosage and Uses

P-Glycoprotein

P-glycoprotein P-glycoprotein (P-gp, MDR1) is a primary active efflux transporter with a molecular weight of 170 kDa, belonging to the ABC superfamily and consisting of 1280 amino acids. P-gp is the product of the -gene (formerly: ). P is for , ABC is for . Occurrence P-glycoprotein is found on various tissues of the human … P-Glycoprotein