Decongestants: Effect, Uses & Risks

Decongestants are drugs that exert a decongestant effect and are used as supportive agents in the treatment of allergic diseases. They are not a uniform group of active substances. The individual substances act according to different mechanisms but with the same result of mucosal decongestion in each case. What are decongestants? Decongestants are drugs that … Decongestants: Effect, Uses & Risks

Cortisone Tablets Effects and Side Effects

Products Cortisone tablets are medicinal products which are intended for ingestion and contain active substances from the group of glucocorticoids. The tablets, water-soluble tablets and sustained-release tablets are usually monopreparations, which are often divisible. Glucocorticoids were first used medicinally in the late 1940s. Structure and properties The glucocorticoids contained in the drugs are derived from … Cortisone Tablets Effects and Side Effects

Caspofungin

Products Caspofungin must be administered as an infusion solution because of its low oral bioavailability (Cancidas, generics). It has been approved in many countries since 2002 and was the first member of the echinocandins. Structure and properties Caspofungin is present in drugs as caspofungin diacetate (C52H88N10O15 – 2C2H4O2, Mr = 1213.42 g/mol), a hygroscopic white … Caspofungin

COVID-19

Symptoms Symptoms of Covid-19 include (selection): Fever Cough (irritating cough or with sputum) Respiratory disorders, shortness of breath, shortness of breath. Feeling sick, fatigue Cold symptoms: runny nose, stuffy nose, sore throat. Pain in the limbs, muscle and joint pain. Gastrointestinal complaints: Diarrhea, nausea, vomiting, abdominal pain. Nervous system: impairment of the sense of smell … COVID-19

Carfilzomib

Products Carfilzomib was approved in many countries in 2015 as a powder for the preparation of an infusion solution (Kyprolis). Structure and properties Carfilzomib (C40H57N5O7, Mr = 719.9 g/mol) exists as a crystalline substance that is practically insoluble in water. It is a peptide derivative, a tetrapeptide epoxyketone. Epoxyketones are derivatives of epoxomicin, a natural … Carfilzomib

Ear Drops

Products In many countries, only a few ear drops are currently on the market. They are also produced in pharmacies themselves. Structure and properties Ear drops are solutions, emulsions, or suspensions containing one or more active ingredients in liquids suitable for use in the ear canal. These include, for example, water, glycols, glycerol, propylene glycol, … Ear Drops

Elotuzumab

Products Elotuzumab was approved in the United States in 2015 and in the EU and Switzerland in 2016 as a powder for the preparation of an infusion solution (Empliciti). Structure and properties Elotuzumab is a humanized IgG1 monoclonal antibody with a molecular weight of 148.1 kDa. It is produced by biotechnological methods. Effects Elotuzumab (ATC … Elotuzumab

Hemorrhoids Causes and Treatment

Symptoms Hemorrhoids are dilations of the vascular cushions in the anal canal. Possible symptoms include: Bleeding, blood on the toilet paper Pressure discomfort, pain, burning, itching. Unpleasant feeling Inflammation, swelling, skin inflammation. Discharge of mucus, oozing Prolapse, protrusion outside the anus (prolapse). Hemorrhoids can be classified according to various criteria. Common is the classification according … Hemorrhoids Causes and Treatment

Altitude Sickness

Symptoms Symptoms of altitude sickness are nonspecific and usually appear 6-10 hours after ascent. However, they can also occur after as little as one hour: Headache Dizziness Sleep disorders Loss of appetite Nausea and vomiting Fatigue and tiredness Rapid heartbeat Accelerated breathing, shortness of breath Severe symptoms: Cough Shortness of breath even at rest Tightness … Altitude Sickness

Lenalidomide

Products Lenalidomide is commercially available in the form of hard capsules (Revlimid). It has been approved in many countries since 2007. Generic versions were registered in 2019. Structure and properties Lenalidomide (C13H13N3O3, Mr = 259.3 g/mol) is a derivative of thalidomide and exists as a racemate. Effects Lenalidomide (ATC L04AX04) has immunomodulatory and antiangiogenic properties. … Lenalidomide

Panobinostat

Products Panobinostat was approved in many countries in 2015 in capsule form (Farydak). Structure and properties Panobinostat (C21H23N3O2, Mr = 349.4 g/mol) is present in the drug as panobinostat lactate, a white to slightly yellow or brownish powder that is sparingly soluble in water. It is an indole, a hydroxamic acid, and a propenamide derivative. … Panobinostat