Amphetamine

Products In many countries, no drugs containing amphetamine are currently registered. The active ingredient is subject to narcotics legislation and requires an aggravated prescription, but is basically not prohibited like other substances from the amphetamine group. In some countries, medicines containing dexamphetamine are on the market, for example in Germany and the USA. Structure and … Amphetamine

Amphetamines

Products Amphetamines are commercially available as drugs in the form of tablets, sustained-release tablets, capsules, and sustained-release capsules. Structure and properties Amphetamines are derivatives of amphetamine. It is a methylphenethylamine structurally related to endogenous monoamines and stress hormones epinephrine and norepinephrine. Amphetamines are racemates and the –enantiomers. Effects Amphetamines have sympathomimetic, central stimulant, bronchodilator, psychoactive, … Amphetamines

Sympatholytics

Products Sympatholytics are commercially available in the form of tablets, capsules, as injectables, and eye drops, among others. Effects Sympatholytics have sympatholytic properties, meaning that they abolish the effects of the sympathetic nervous system, a portion of the autonomic nervous system. Their effects are usually due to direct antagonism at adrenoceptors. Indirect sympatholytics reduce the … Sympatholytics

Adenylyl Cyclases: Function & Diseases

Adenylyl cyclases belong to the lyases as a class of enzymes. Their function is to catalyze cyclic cAMP by cleaving P-O bonds from ATP. In doing so, they trigger a signaling cascade that is responsible for many different processes in the organism. What is an adenylyl cyclase? Adenylyl cyclases mediate effects of hormones or other … Adenylyl Cyclases: Function & Diseases

Fluvoxamine: Effects, Uses & Risks

Fluvoxamine is an antidepressant that belongs to the group of selective serotonin reuptake inhibitors. In Germany, the active ingredient has been approved for the treatment of depression and obsessive-compulsive disorder, but it is also frequently used to treat anxiety and panic disorders and post-traumatic stress disorder. When using the drug, interactions with other medications such … Fluvoxamine: Effects, Uses & Risks

Hydralazine: Effects, Uses & Risks

Hydralazine is a drug that has a vasodilator effect. It is used to treat heart failure as well as hypertension during pregnancy. What is hydralazine? Hydralazine belongs to the group of vasodilators. These are vasodilating agents that are used to lower high blood pressure. In Europe, however, the related dihydralazine is more commonly used. The … Hydralazine: Effects, Uses & Risks

Antiallergics

Products Anti-allergy medications are available in numerous dosage forms. These include tablets, capsules, solutions, suspensions, nasal sprays, eye drops, inhalation preparations, and injectables. Structure and properties Antiallergic drugs do not have a uniform chemical structure. However, several groups within the class can be identified (see below). Effects Antiallergic drugs have antiallergic, antiinflammatory, immunosuppressive, antihistamine, and … Antiallergics

Antiasthmatics

1. symptom treatment Beta2-sympathomimetics are derived from epinephrine. They selectively stimulate the adrenergic β2-receptors of bronchial muscles and thus have a bronchospasmolytic effect. For rapid symptom relief, fast-acting agents are usually administered by inhalation, for example, with a metered-dose inhaler or a powder inhaler. They should be used only when needed. An increase in administration … Antiasthmatics

Promethazine

Products In many countries, drugs containing promethazine are currently no longer on the market. The last product to be withdrawn from the market was Rhinathiol promethazine with the expectorant carbocisteine on January 31, 2009. However, medicines are still available in many countries. The original drug is Phenergan. Promethazine was developed in the 1940s at Rhône-Poulenc, … Promethazine

Beta2-Sympathomimetics

Products Beta2-sympathomimetics are usually commercially available as inhalation preparations (powders, solutions) administered with an inhaler, for example, metered-dose inhaler, diskus, Respimat, Breezhaler, or Ellipta. There are few drugs on the market that can be given perorally. Structure and properties Beta2-sympathomimetics are structurally related to the natural ligands epinephrine and norepinephrine. They may exist as racemates … Beta2-Sympathomimetics

Beta Blocker Effects and Side Effects

Products Beta-blockers are available in many countries in the form of tablets, film-coated tablets, sustained-release tablets, as capsules, solution, eye drops, and as injection and infusion solutions. Propranolol (Inderal) was the first representative of this group to appear on the market in the mid-1960s. Today, the most important active ingredients include atenolol, bisoprolol, metoprolol and … Beta Blocker Effects and Side Effects