Ergotamine: Effects, Usage, Risks

How ergotamine works Ergotamine is an active ingredient from the group of ergot alkaloids. After ingestion, it acts in the body in a variety of ways. Its effectiveness in migraine is mainly due to the fact that ergotamine has a similar structure to the body’s own messenger substance serotonin. The active ingredient therefore also binds … Ergotamine: Effects, Usage, Risks

Azithromycin

Products Azithromycin is commercially available in the form of film-coated tablets, powder for preparation of a suspension, and granules (Zithromax, generic). Furthermore, a granule for the preparation of a sustained-release oral suspension is available (Zithromax Uno). Eye drops have also been released in some countries. Azithromycin has been approved in many countries since 1992. Structure … Azithromycin

Ergotamine

Products In many countries, drugs containing ergotamine are currently no longer on the market. The active ingredient was available in tablet form in combination with caffeine, among other products (Cafergot), but was withdrawn from the market in 2014. Products containing ergotamine were first launched in the 1920s (Gynergen). Structure and properties Ergotamine (C33H35N5O5, Mr = … Ergotamine

Medicinal Mushrooms

Products Medicinal mushrooms are commercially available, for example, in the form of capsules, tablets and as powders as dietary supplements or as individually prepared mixtures. Also used are the pure ingredients that are extracted, synthetically produced or semi-synthetically modified. These are usually registered as medicinal products. About mushrooms Fungi are a very diverse group of … Medicinal Mushrooms

Eletriptan

Products Eletriptan is commercially available in the form of film-coated tablets (Relpax, generics). It has been approved in many countries since 2000. Structure and properties Eletriptan (C22H26N2O2S, Mr = 382.5 g/mol) is a lipophilic methylpyrrolidinyltryptamine substituted with a sulfonylbenzene. It is present in drugs as eletriptan hydrobromide, a white powder that is readily soluble in … Eletriptan

Ergotism: Causes, Symptoms & Treatment

Ergotism is poisoning by ergot alkaloids such as ergotamine or ergometrine, which are found in ergot fungi and are used as drugs nowadays. The symptomatology focuses on massive circulatory disturbances with death of arms or legs, which can lead to death. What is ergotism? Ergotism actually belongs to the category of “medical history“: as poisoning … Ergotism: Causes, Symptoms & Treatment

Erythromycin

Products Erythromycin is commercially available for peroral administration in tablet and granular form (Erythrocin / Erythrocin ES). This article refers to the drugs intended for ingestion. Erythromycin was first approved in the 1950s. Structure and properties Erythromycin is a natural substance produced by the bacterium (formerly: ). In oral medications, it is present as erythromycin … Erythromycin

Almotriptan for Migraine Headache

Products Almotriptan is commercially available in the form of film-coated tablets (Almogran). It has been approved in many countries since 2004. Structure and properties Almotriptan (C17H25N3O2S, Mr = 335.5 g/mol) is present in drugs as almotriptan-D,L-hydrogenmalate, a white to slightly yellowish crystalline powder that is soluble in water. Effects Almotriptan (ATC N02CC05) has vasoconstrictive, analgesic, … Almotriptan for Migraine Headache

Almotriptan: Effects, Uses & Risks

Almotriptan is an acute medication for migraine. The drug, produced by the Spanish pharmaceutical company Almirall, is offered in Germany by different companies and is also available without a prescription in pharmacies. What is almotriptan? Almotriptan is an acute medication for migraine. A vasoconstrictor, analgesic, and anti-inflammatory agent in the triptan group, almotriptan is used … Almotriptan: Effects, Uses & Risks

Amlodipine (Norvasc)

Products Amlodipine is commercially available in tablet form (Norvasc, generic). It has been approved in many countries since 1990. Amlodipine is also combined fixed with the following agents: Aliskiren, atorvastatin, perindopril, telmisartan, valsartan, olmesartan, hydrochlorothiazide, and indapamide. Structure and properties Amlodipine (C20H25ClN2O5, Mr = 408.9 g/mol) has a chiral center and is a racemate. It … Amlodipine (Norvasc)

Ergot Alkaloids

Structure and properties Depending on the side chains, ergot alkaloids are classified into two different groups: Ergometrine-type ergot alkaloids (e.g., ergometrine, methylergometrine). Peptide-type ergot alkaloids (e.g., ergotamine, ergotoxine, bromocriptine). Effects Ergot alkaloids exhibit the following effects in varying degrees: Partial agonists at alpha-adrenoreceptors. Partial agonists at serotonin receptors Stimulation of dopamine receptors Contraction of vascular … Ergot Alkaloids