How fentanyl works Fentanyl is a strong analgesic from the group of opioids. Its analgesic potency is about 125 times that of morphine. The nerves in the body conduct stimuli, including pain stimuli, from almost every part of the body to the central nervous system (= brain and spinal cord). The intensity of the stimulus … Fentanyl: Effects, areas of application, side effects
Symptoms Drug-induced prolongation of the QT interval can rarely lead to severe arrhythmias. This is polymorphic ventricular tachycardia, known as torsade de pointes arrhythmia. It can be seen on the ECG as a wave-like structure. Due to the dysfunction, the heart cannot maintain blood pressure and can only pump insufficient blood and oxygen to the … Prolongation of the QT Interval
Symptoms After the initial clinical manifestation in the form of chickenpox, the virus remains in a latent stage in the dorsal root ganglia for life. Reactivation of the virus occurs particularly in the presence of weakened immune defenses. Vesicles with cloudy contents form in the area supplied by the infected nerve, e.g. on the trunk … Shingles: Causes, Symptoms, Treatment, Prevention
Fentanyl was developed in 1960 by Paul Janssen and was the first anilinopiperidine at that time. Some modifications to the molecular formula have since allowed some derivatives to be developed from fentanyl that are more controllable. What is fentanyl? Fentanyl is used in anesthesia as an analgesic and in the treatment of chronic pain. Fentanyl … Fentanyl: Effects, Uses & Risks
Products Propofol is commercially available as an emulsion for injection or infusion (Disoprivan, generic). It has been approved in many countries since 1986. Structure and properties Propofol obtained by distillation (C12H18O, Mr = 178.3 g/mol, 2,6-diisopropylphenol) is a colorless to pale yellow, clear liquid that is sparingly soluble in water and miscible with hexane and … Propofol (Diprivan): Drug Effects, Side Effects, Dosage and Uses
Products The narcotics are a group of centrally acting drugs and substances, which are strongly regulated and controlled by the state respectively by the drug and health authorities. This is primarily to prevent abuse and to protect the population from the undesirable effects and addiction. Certain narcotics – for example, many potent hallucinogens – are … Narcotics Effects and Side Effects
Products In many countries, no drugs containing carfentanil are on the market. The active ingredient is used in veterinary medicine (Wildnil). Legally, it belongs to narcotics. Structure and properties Carfentanil (C24H30N2O3, Mr = 394.5 g/mol) is structurally closely related to fentanyl, being 4-methoxycarbonylfentanyl. Carfentanil citrate is present in pharmaceuticals. The active ingredient was developed at … Carfentanil
Nalbuphine is an analgesic agent that belongs to the opioid group. It is used for short periods to relieve moderate to acute pain and is primarily administered as a solution with varying levels of active ingredient. In addition, the substance is also used in anesthesia. What is nalbuphine? Nalbuphine is a medicinal substance belonging to … Nalbuphine: Effects, Uses & Risks
Products Transdermal patches are approved as medicinal products. They offer themselves as an alternative to other modes of application such as peroral and parenteral administration. The first products were launched in the 1970s. Structure and properties Transdermal patches are flexible pharmaceutical preparations of varying sizes and thinness that contain one or more active ingredients. They … Transdermal Patches
Fentanyl is a very strong analgesic similar to opium that is covered by the Narcotics Act in Germany. Because of its high analgesic and strong sedative effect, the opioid is used intravenously as an anesthetic, especially during surgery. Because of its rapid onset of action, fentanyl is also commonly used in emergency medicine. As a … Fentanyl: Effects, Dosage, Side Effects
Products Alfentanil is commercially available as a solution for injection (Rapifen). It has been approved in many countries since 1983. Structure and properties Alfentanil (C21H32N6O3, Mr = 416.5 g/mol) is a 4-anilidopiperidine and a tetrazole derivative. It is present in the drug as alfentanil hydrochloride, a white powder that is readily soluble in water. The … Alfentanil
Products Nalbuphine is commercially available as a solution for injection (Nalbuphine OrPha). It has been approved in many countries since 2004. Structure and properties Nalbuphine (C21H27NO4, Mr = 357.4 g/mol) is a morphine derivative structurally related to naloxone and oxymorphone. It is present in drugs as nalbuphine hydrochloride. Effects Nalbuphine (ATC N02AF02) has analgesic properties. … Nalbuphin
