Products Acetylsalicylic acid is commercially available in the low dosage of 100 mg in the form of enteric-coated film-coated tablets (Aspirin Cardio, generics; in Germany and Austria, Aspirin Protect). The drug has been approved in many countries since 1992. Aspirin Cardio 300 mg is also used. In the United States, drugs with 81 mg (= … Acetylsalicylic Acid 100 mg
Products Indapamide is commercially available as tablets and capsules alone in sustained-release formulations (Fludex SR, generic) and in combination with the ACE inhibitor perindopril (Coversum N Combi, generic). A fixed combination of perindopril, indapamide, and amlodipine is also available (Coveram plus). Indapamide was developed in the 1970s and has been approved in many countries since … Indapamide
Products Selenium disulfide is commercially available as a shampoo (suspension) in fixed combination with sulfur (ectoselen). It has been approved in many countries since 1952. Selsun has not been marketed since 2019. Structure and properties Selenium disulfide (SeS2, Mr = 143.1 g/mol) exists as a yellow-orange to reddish-brown powder that is practically insoluble in water. … Selenium Disulfide
Products Dexketoprofen is commercially available as film-coated tablets and as a solution for injection (Ketesse). It has been approved in many countries since 2000. In 2017, a fixed combination with tramadol was registered; see Tramadol Dexketoprofen (Skudexa). Structure and properties Dexketoprofen (C16H14O3, Mr = 254.3) is the active -enantiomer of ketoprofen, which exists as a … Dexketoprofen
Products Atorvastatin is commercially available in the form of film-coated tablets (Sortis, generic, auto-generic). It has been approved in many countries since 1997. Atorvastatin is also available as a fixed combination with ezetimibe; see Atorvastatin and Ezetimibe. Structure and Properties Atorvastatin (C33H35FN2O5, Mr = 558.64 g/mol) is present in drugs as atorvastatin calcium trihydrate, (atorvastatin)2– … Atorvastatin
Products The fixed combination Xultophy was approved in many countries and in the EU in 2014 as an injection solution in a prefilled pen. It was released in the United States in 2016. Structure and properties IDegLira is the name given to the combination of the insulin insulin degludec (IDeg, Tresiba) with the GLP-1 receptor … IDegLira
Products Opicapone was approved in the EU in 2016 and in many countries in 2018 in hard capsule form (Ongentys). Structure and properties Opicapone (C15H10Cl2N4O6, Mr = 413.2 g/mol) is an oxadiazole derivative with a pyridine–oxide at position 3. The compound was designed with the goal of developing an effective and safer COMT inhibitor. This … Opicapon
Products In many countries, urea ointment 40% is sold as a medical product (Onyster). A urea ointment can also be prepared in a pharmacy, for example as an extemporaneous formulation (see below). Bayer discontinued the sale of the Canesten nail set in 2016. In Germany and Austria, the urea ointment also contains the azole antifungal … Urea Ointment
Products Tezacaftor was approved in the US and EU in 2018 and in many countries in 2019 in fixed combination with previously registered ivacaftor in film-coated tablet form (Symdeko). In 2020, a fixed combination with tezacaftor, elexacaftor, and ivacaftor was approved (Trikafta). Structure and properties Tezacaftor (C26H27F3N2O6, Mr = 520.5 g/mol) exists as a white … Tezacaftor
Products Oxycodone is commercially available in the form of sustained-release tablets, capsules, melting tablets, as an injectable, and drops (including Oxycontin, Oxynorm, and generics). It has been used medicinally for decades. In the U.S., it is also used as a fix in combination with other analgesics such as acetaminophen (e.g., Percocet). Oxycodone is also available … Oxycodone: Drug Effects, Side Effects, Dosage and Uses
Products The fixed combination Targin with the active ingredients oxycodone and naloxone was approved in many countries in 2009. In other countries, the drug is also known as Targinact or Targiniq. In 2016, generic versions were approved in many countries. They went on sale in 2018. Structure and properties Oxycodone (C18H21NO4, Mr = 315.4 g/mol) … Oxycodone, Naloxone
Products Lumefantrine is commercially available in tablet form as a fixed combination with artemether (Riamet). It has been approved in many countries since 1999. Structure and properties Lumefantrine (C30H32Cl3NO, Mr = 528.9 g/mol) is a racemate. It exists as a yellow crystalline powder that is insoluble in water. Effects Lumefantrine (ATC P01BF01) has antiparasitic properties. … Lumefantrine