Products Azelaic acid is commercially available as gel and cream (Skinoren). It has been approved in many countries since 1990. Structure and properties Azelaic acid (C9H16O4, Mr = 188.2 g/mol) is a saturated dicarboxylic acid. It exists as a white, odorless, crystalline solid that is poorly soluble in water at 20°C but dissolves well in … Azelaic Acid for Skin Problems
Products Ingenol mebutate was commercially available as a gel (Picato). It was approved in many countries in 2013, and in the EU and the U.S. as early as 2012. In 2020, approval was withdrawn because an increased risk of skin cancer was observed with the treatment. Structure and properties Ingenol mebutate (C25H34O6, Mr = 430.5 … Ingenol Mebutate
Products Benzalkonium chloride is commercially available as an active pharmaceutical ingredient in the form of lozenges, as a gargling solution, as a gel and as a disinfectant, among others. As a preservative, it is commonly added in pharmaceuticals to eye drops, nasal sprays, nose drops and inhalation solutions for asthma and COPD treatment. It is … Benzalkonium Chloride
Products Crospovidone (polyvinylpolypyrrolidone) is found in many drugs as an excipient, especially in tablets. Not to be confused with copovidone. Structure and properties Crospovidone is a cross-linked homopolymer of 1-ethenylpyrrolidin-2-one. It exists as a white to yellowish-white hygroscopic powder or as a leaflet and is practically insoluble in water. This is in contrast to the … Crospovidone
Products Gelatin is available as a pure substance in grocery stores and in pharmacies or drugstores. It is found in many processed foods, pharmaceuticals, and sweets, among other products. Structure and properties Gelatin is a purified mixture of proteins obtained by either partial acid, alkaline, or enzymatic hydrolysis of collagen. Hydrolysis results in gelling and … Gelatin
Products Ketoprofen is commercially available as a gel (Fastum). It has been approved in many countries since 1992 and in the EU since 1978. The -enantiomer dexketoprofen is available as tablets and as a solution for injection (Ketesse). This article refers to external use. After the safety of topical ketoprofen was questioned in France in … Ketoprofen
Products Calcipotriol is commercially available as a fixed combination with betamethasone dipropionate as a gel, ointment, and foam (Xamiol, Daivobet, Enstilar, generics). Structure and properties Calcipotriol (C27H40O3, Mr = 412.60 g/mol) is a synthetic derivative of natural vitamin D3 (cholecalciferol). It exists as a white crystalline powder. Effects Calcipotriol (ATC D05AX02) has antiproliferative, anti-inflammatory, and … Calcipotriol
Symptoms Local skin reactions such as itching, inflammation, redness, and blistering occur acutely, especially at the sites of contact with the trigger. In the chronic stage, dry, scaly and cracked skin is often observed, e.g. in the form of chronic hand eczema. Affected areas include the hands, abdomen and earlobes. The rash can also appear … Metal Allergy
Products Isotretinoin is commercially available in capsule and gel form (Roaccutane, generics). It has been approved in many countries since 1983 (United States: 1982, Accutane). This article refers to the capsules. See also under isotretinoin gel. Structure and properties Isotretinoin (C20H28O2, Mr = 300.4 g/mol) exists as a yellow to light orange crystalline powder that … Isotretinoin
Products Mouth gels are available in pharmacies and drugstores from a variety of suppliers. Structure and properties An oral gel is a gel, that is, a gelled liquid prepared with appropriate gelling agents, which is intended for use in the oral cavity. The active ingredients it contains include, for example: Salicylates such as choline salicylate … Mouth Gels
Products Diphenhydramine is commercially available in tablet, drop, and gel forms (e.g., Benocten, Nardyl Sleep, Fenipic plus), among others. It is also known as Benadryl in some countries. Diphenhydramine was developed in the 1940s. It is also a component of the active ingredient dimenhydrinate. Structure and properties Diphenhydramine (C17H21NO, Mr = 255.4 g/mol) is present … Diphenhydramine
Products Heparin sodium is applied primarily as a gel or ointment (eg, HepaGel, Lioton, Demovarin, combination products). This article refers to topical therapy. Heparin sodium is also injected parenterally. Structure and properties Heparin sodium is the sodium salt of a sulfated glycosaminoglycan found in mammalian tissues. It is obtained from the intestinal mucosa of pigs, … Heparin Sodium