Products Carmenthin and Gaspan were approved in many countries in 2019 in the form of enteric-coated soft capsules. In Germany, the drug has been on the market for some time. Structure and properties The capsules contain two essential oils, peppermint oil and caraway oil. This combination is also known as menthacarin. The enteric-coated capsules release … Peppermint Oil, Caraway Oil
Products Antacids are commercially available in the form of lozenges, chewable tablets, as a powder, and as a gel (suspension) for oral use, among others. Well-known brands in many countries include Rennie, Alucol, and Riopan. The first medicines were developed as early as the 19th century. Structure and properties The drugs contain active ingredients that … Antacids to Neutralise Stomach Acid
Symptoms Globus syndrome1 manifests as the sensation of having a lump, foreign body, uncomfortable feeling, or tightness/pressure in the throat. On medical examination, no foreign body or tissue overgrowth can be detected. The discomfort occurs primarily with empty swallowing and improves with eating or drinking. Difficulty swallowing and pain, on the other hand, do not … Globe Syndrome
Products Cimetidine was commercially available in the form of film-coated tablets (Tagamet). Currently, there are no longer any human medicines registered with the active ingredient in many countries. Cimetidine was developed in the 1960s and 1970s under the leadership of Sir James Black as the first wirsktoff from the group of H2 receptor antagonists and … Cimetidine
Symptoms The leading symptoms of stomach burning include an uncomfortable burning sensation behind the breastbone and acid regurgitation. The burning sensation occurs primarily after eating, and pain along the esophagus may radiate. Other accompanying symptoms include hoarseness, coughing, nausea, difficulty swallowing, sleep disturbances, respiratory problems, a foreign body sensation in the throat, and enamel changes. … Stomach Burn
Products Proton pump inhibitors (PPIs) are commercially available in many countries in the form of film-coated tablets, MUPS tablets, capsules, as granules for preparation of an oral suspension, and as injectable and infusion preparations. The first active ingredient from this group to be approved in many countries was omeprazole (Antra, Losec), developed by Astra in … Proton Pump Inhibitors
Products No finished drug products containing roxatidine are commercially available in many countries. Structure and properties Roxatidine (C17H26N2O3, Mr = 306.4 g/mol) is present in the drug as roxatidine acetate, a prodrug that is metabolized in the body to the active drug. Effects Roxatidine (ATC A02BA06) inhibits the secretion of gastric acid and pepsin in … Roxatidine
Products Nizatidine is not commercially available in many countries and Germany. In the United States, capsules and film-coated tablets, among other products, have been on the market since 1992. Structure and properties Nizatidine (C12H21N5O2S2, Mr = 331.5 g/mol) is a thiazole derivative and an organic cation. It exists as a white crystalline substance that is … Nizatidine
Products Famotidine is not commercially available in many countries. In Germany and other countries, it is available in the form of film-coated tablets. Structure and properties Famotidine (C8H15N7O2S3, Mr = 337.4 g/mol) exists as a white to yellowish-white crystalline powder or as crystals and is very sparingly soluble in water. It is a thiazole derivative … Famotidine
Products Ranitidine was commercially available in the form of film-coated tablets, effervescent tablets, and as a solution for injection and had been approved since 1981 (Zantic, generic). Currently, drugs containing ranitidine are no longer available in many countries. Starting in 1996, tablets for self-medication with 75 mg were released. However, they are now also no … Ranitidine: Drug Effects, Side Effects, Dosage and Uses
Products H2 receptor antagonists were commercially available in many countries in tablet, effervescent tablet, and solution for injection forms, among others. Currently, no more drugs are available. Due to proton pump inhibitors (PPI), H2 antagonists have become less important. The first active ingredient, cimetidine (Tagamet), was developed in the 1960s and 70s under the leadership … H2 Receptor Antagonists
Products No finished drug products containing lafutidine are commercially available in many countries. Structure and properties Lafutidine (C22H29N3O4S, Mr = 431.5 g/mol) Effects Lafutidine (ATC A02BA08) inhibits gastric acid and pepsin secretion in the stomach. Effects are due to antagonism at histamine H2 receptors. Indications For the treatment of gastric acid-associated disorders (eg, gastric distention, … Lafutidin
