Hexoprenaline

Products Hexoprenaline is commercially available as a solution for injection (Gynipral). It has been approved in many countries since 1984. Approval for the tablets was revoked on Dec. 31, 2013. This due to the potential cardiovascular side effects that may occur in the mother and child. Structure and properties Hexoprenaline (C22H32N2O6, Mr = 420.5 g/mol) … Hexoprenaline

Letrozole

Products Letrozole is commercially available in the form of film-coated tablets (Femara, generic). It has been approved in many countries since 1997. Structure and properties Letrozole (C17H11N5, Mr = 285.3 g/mol) is a nonsteroidal aromatase inhibitor. It exists as a white to yellowish crystalline powder that is nearly odorless and virtually insoluble in water. Letrozole … Letrozole

Menopausal Symptoms

Symptoms Menopausal symptoms are very individual and vary from woman to woman. The most common possible disorders include: Cycle irregularities, change in menstruation. Vasomotor disorders: Flushes, night sweats. Mood swings, irritability, aggressiveness, sensitivity, sadness, difficulty concentrating, anxiety, fatigue. Sleep disorders Changes in skin, hair and mucous membranes: hair loss, vaginal atrophy, vaginal dryness, dry skin, … Menopausal Symptoms

Cimicifuga Effects and Side Effects

Products Cimicifuga extracts are commercially available from various suppliers (e.g., Cimifemin Zeller, Femicin, Climavita). Stem plant The parent plant is the perennial Black cohosh L. of the buttercup family, native to eastern North America and traditionally used by Native Americans. Medicinal drug The rootstock, the cimicifugarhizome (Cimicifugae racemosae rhizoma), is used as the medicinal drug. … Cimicifuga Effects and Side Effects

Danazol

Products Danazol was commercially available in many countries in the form of capsules and had been approved since 1977 (Danatrol). No finished drug products have since been registered. Structure and properties Danazol (C22H27NO2, Mr = 337.5 g/mol) is an isoxazole derivative of ethisterone related to testosterone. Danazol exists as a white to slightly yellow crystalline … Danazol

Strontium-89

Products Strontium-89 was commercially available as an injectable (Metastron). It is no longer available. Structure and properties The strontium isotope strontium-89 is present in drugs as strontium chloride. Effects Strontium-89 (ATC V10BX01) has analgesic properties. It behaves similarly to calcium in the body and is predominantly accumulated in active bone tissue. It is a beta … Strontium-89

Bazedoxifene

Products Bazedoxifene is commercially available in the form of film-coated tablets (Conbriza). It has been approved in many countries since 2010. In 2015, a fixed combination with conjugated estrogens was registered (Duavive). This article refers to monotherapy. Structure and properties Bazedoxifene (C30H34N2O3, Mr = 470.60 g/mol) is a nonsteroidal selective estrogen receptor modulator developed from … Bazedoxifene

Hot flushes in men

Introduction The term hot flashes usually refers to a sudden feeling of warmth or heat, usually starting in the area of the torso or neck and continuing towards the head. Usually, this sensation is accompanied by increased sweating and a higher heart rate as well as a noticeable throbbing in the chest. The term describes … Hot flushes in men

Diagnosis | Hot flushes in men

Diagnosis Hot flashes are a subjective sensation in themselves and cannot be objectified. For a diagnosis, the cause of the hot flushes should therefore be found out. For this purpose, a detailed medical consultation is recommended in order to discuss the accompanying symptoms, the duration of the complaints and the habits of the person concerned. … Diagnosis | Hot flushes in men

Prognosis | Hot flushes in men

Prognosis Hot flashes should improve significantly once their triggers are treated or eliminated.Which measures can contribute to this is described above – but sometimes it is also a matter of “self-limiting” complaints: This means that the hot flushes disappear after a while without any further measures. If this is not the case, or if measures … Prognosis | Hot flushes in men

Bicalutamide

Products Bicalutamide is commercially available in the form of film-coated tablets (Casodex, generics). It has been approved in many countries since 1995. Structure and properties Bicalutamide (C18H14F4N2O4S, Mr = 430.37 g/mol) is a racemate, with the -enantiomer being almost exclusively responsible for the antiandrogenic effect. It exists as a white powder that is practically insoluble … Bicalutamide