Chickenpox (Varicella): Causes

Pathogenesis (development of disease)

Varicella-zoster virus (synonyms: varicella-zoster virus (VZV) – also spelled varicella-zoster virus and referred to as human herpes virus-3)) is transmitted aerogenically or as a smear infection and enters the body through the mucous membranes or conjunctiva. From there, it travels to the lymph nodes, where it multiplies greatly and then primarily affects the liver and spleen. In a second viremia (generalization phase of a cyclic viral infection, which is associated with the settlement, multiplication and spread of the viruses through the bloodstream), it enters the whole body. Due to the cytopathology of the virus, the described skin changes occur. Diaplacental (passing through the placenta) infection is possible.

Etiology (causes)

Behavioral causes

  • Contact with persons with chickenpox
  • Insufficient hygiene