Piretanide

Products Piretanide is commercially available in tablet form (Trialix + ramipril). It has been approved in many countries since 1985. In many countries, only the fixed combination with the ACE inhibitor ramipril is currently available. Structure and properties Piretanide (C17H18N2O5S, Mr = 362.40 g/mol) has structural similarities to other loop diuretics and is a sulfonamide. … Piretanide

Gout

Synonyms in a broader sense Medical: Hyperuricemia “Zipperlein”, attack of gout, Podagra, arthritis urica Definition Gout Gout is a metabolic disorder in which uric acid crystals are deposited mainly in the joints. Uric acid is produced in the human body, among other things, during cell death and the breakdown of cell components (e.g. the DNADNS … Gout

Treatment of gout | Gout

Treatment of gout The therapy for gout starts with a healthy diet. A diet low in purine is recommended, since purines are metabolized in the human body to uric acid. In order to adjust the increased uric acid mirror in the long run, medicines are prescribed by the physician, which restrain the uric acid formation. … Treatment of gout | Gout

Gout attack

Introduction Gout is a disease that is due to a malfunction of the purine metabolism and runs in waves. Patients suffering from gout should consult a physician promptly and initiate appropriate treatment, as this disease can lead to the deposition of uric acid crystals (so-called urate) in various joints and tissues if insufficient therapy is … Gout attack

Symptoms | Gout attack

Symptoms The symptoms of an acute attack of gout can vary from patient to patient both in intensity and duration. However, pain in the affected joints and in the surrounding tissue are among the typical symptoms of an acute attack of gout. In addition, all classic signs of inflammation can be detected in the joints. … Symptoms | Gout attack

Therapy | Gout attack

Therapy The main aim of the therapy of a gout attack is both the rapid relief of the pain symptoms and the inhibition of the spread of inflammatory processes in the area of the affected joints. The treatment of an acute attack of gout is generally carried out by the administration of various drugs. In … Therapy | Gout attack

Diazoxide

Products Diazoxide is commercially available in capsule form (Proglicem). It has been approved in many countries since 1978. Structure and properties Diazoxide (C8H7ClN2O2S, Mr = 230.7 g/mol) exists as a white powder that is practically insoluble in water. It is a benzothiadiazine derivative and structurally related to the thiazides, but is not diuretic. Effects Diazoxide … Diazoxide

Therapy for gout

A distinction must be made here between the therapy of acute attacks of gout and the therapy of increased uric acid (hyperuricemia). The aim of the treatment of the acute attack of gout is to relieve pain and contain the inflammatory reaction. In the past, colchicine, the poison of the autumn timeless people, was mostly … Therapy for gout

Attack of gout

Causes The cause of a gout attack is the excessive accumulation of uric acid in the blood, also known as hyperuricemia. This is usually caused by a diet rich in purine, as well as the consumption of alcoholic and fruit beverages and foods. Among the rarer causes are genetic defects and syndromes with the lack … Attack of gout