Detomidine

Products Detomidine is commercially available as a solution for injection and a gel (Domosedan, Equisedan, Medesedan). It has been approved in many countries since 1990. Structure and properties Detomidine (C12H14N2, Mr = 186.3 g/mol) is an imidazole derivative. It is structurally closely related to medetomidine. Effects Detomidine (ATCvet QN05CM90) is sedative, analgesic, and muscle relaxant. … Detomidine

Butoconazole

Products Butoconazole vaginal cream is no longer available in many countries (Gynazole). It is on the market in other countries. Structure and properties Butoconazole (C19H17Cl3N2S, Mr = 411.8 g/mol) is present in drugs as butoconazole nitrate, a white crystalline powder that is practically insoluble in water. It is a chlorinated imidazole derivative. Effects Butoconazole (ATC … Butoconazole

Flumazenil

Products Flumazenil is commercially available as a solution for injection (Anexate, generics). It was developed at Roche and has been approved in many countries since 1986. Structure and properties Flumazenil (C15H14FN3O3, Mr = 303.3 g/mol) exists as a white crystalline powder that is very sparingly soluble in water. It has a comparable structure to other … Flumazenil

Secnidazole

Products Secnidazole was approved in the United States in 2017 in granular form (Solosec). The substance is not new; it was developed in the 20th century. Structure and properties Secnidazole (C7H11N3O3, Mr = 185.2 g/mol) is an imidazole derivative (nitroimidazole) nitrated at position 5. It is a prodrug that is activated in bacteria. Effects Secnidazole … Secnidazole