Products Fluconazole is commercially available in capsule form, as a powder for suspension, and as an infusion solution (Diflucan, generic). It has been approved in many countries since 1989. Structure and properties Fluconazole (C13H12F2N6O, Mr = 306.3 g/mol) is a fluorinated triazole derivative. It exists as a white, crystalline and hygroscopic powder that is sparingly … Fluconazole
Products Brentuximab vedotin is commercially available as a powder for the preparation of an infusion solution (Adcetris). It has been approved in many countries since 2013. Structure and properties Brentuximab vedotin is an anti-CD30 antibody-drug conjugate, a recombinant chimeric lgG1 antibody conjugated to the cytotoxic agent monomethylauristatin E (MMAE, C39H67N5O7, Mr = 718.0 g/mol). It … Brentuximab Vedotin
Products Levofloxacin is commercially available as film-coated tablets and as an infusion solution (Tavanic, generic). It was approved in many countries in 1998. Generics came on the market in 2011. In 2018, a solution for a nebulizer was registered (Quinsair). The racemate ofloxacin is available as tablets (Tarivid), eye drops, and eye ointment (Floxal). Structure … Levofloxacin
Products Levosimendan is commercially available as a concentrate for the preparation of an infusion solution (Simdax). It was approved in many countries in 2013. Structure and properties Levosimendan (C14H12N6O, Mr = 280.3 g/mol) Effects Levosimendan (ATC C01CX08) has positive inotropic and vasodilatory properties. The effects are due to binding to cardiac troponin C. This increases … Levosimendan
Products Avelumab was approved in the United States, the EU, and many countries in 2017 as a concentrate for the preparation of an infusion solution (Bavencio). Structure and properties Avelumab is a human IgG1λ monoclonal antibody against programmed cell death ligand 1 (PD-L1) with a molecular weight of 147 kDa. It is produced by biotechnological … Avelumab
Products Delafloxacin was approved in the United States in 2017, in the EU in 2019, and in many countries in 2020 as a powder for a concentrate for solution for infusion and in tablet form (Quofenix). Structure and properties Delafloxacin (C18H12ClF3N4O4, Mr = 440.8 g/mol) belongs to the group of fluoroquinolones. It is present in … Delafloxacin
Products Clarithromycin is commercially available as film-coated tablets, sustained-release tablets, oral suspension, and powder for solution for infusion (Klacid, generics). It has been approved in many countries since 1990. Clarithromycin should not be confused with ciprofloxacin. Structure and properties Clarithromycin (C38H69NO13, Mr = 747.96 g/mol) exists as a white crystalline powder that is practically insoluble … Clarithromycin
