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Psychotropic Drugs: Types, Effects, Indications, Dosage

Products Psychotropic drugs are commercially available, for example, in the form of tablets, melting tablets, dragées, capsules, drops, solutions and as injectables. The first psychotropic drugs were developed in the 1950s. Structure and properties Psychotropic drugs vary chemically, but groups with a common structure can be identified, for example, the benzodiazepines, the phenothiazines, and the … Psychotropic Drugs: Types, Effects, Indications, Dosage

Ropinirole

Products Ropinirole is commercially available in the form of film-coated tablets (Adartrel, Requip, generic). It has been approved in many countries since 1996. Structure and properties Ropinirole (C16H24N2O, Mr = 260.4 g/mol) is a non-ergoline dopamine agonist and a dihydroindolone derivative. It is present in drugs as ropinirole hydrochloride, a white to yellow powder that … Ropinirole

Baclofen

Products Baclofen is commercially available as in tablet form and as a solution for injection (Lioresal, generics). It has been approved in many countries since 1970. Structure and properties Baclofen (C 10 H 12 ClNO 2 , M r = 213.7 g/mol) exists as a white and odorless powder that is sparingly soluble in water. … Baclofen

Chlorpromazine

Products Chlorpromazine was commercially available in various oral and parenteral dosage forms (e.g., Chlorazine, Thorazine, Largactil, Megaphene). It was first used in the 1950s as one of the first synthetic antipsychotics. Today, it is no longer a registered drug in many countries. In some countries, chlorpromazine is still on the market. Structure and properties Chlorpromazine … Chlorpromazine

Lacosamide

Products Lacosamide is commercially available as film-coated tablets, syrup, and infusion solution (Vimpat). It has been approved in many countries since 2009. Structure and properties Lacosamide (C13H18N2O3, Mr = 250.3 g/mol) is present as a white to slightly yellow powder and is sparingly soluble in water. It is present in the drug as a pure … Lacosamide

Topiramate

Products Topiramate is commercially available in tablet and capsule form (Topamax, generic). It has been approved in many countries and in the United States since 1996. Structure and properties Topiramate (C12H21NO8S, Mr = 339.36 g/mol) lies as a white powder with a bitter taste that is soluble in water. It is a sulfamate-substituted monosaccharide. Effects … Topiramate

Gabapentin: Drug Effects, Side Effects, Dosage and Uses

Products Gabapentin is commercially available in the form of capsules and film-coated tablets (Neurontin, generic). It has been approved in many countries since 1994. Pfizer launched pregabalin (Lyrica) as its successor in 2004. Structure and properties Gabapentin (C 9 H 17 NO 2 , M r = 171.2 g/mol) is structurally a GABA analog and … Gabapentin: Drug Effects, Side Effects, Dosage and Uses

Brexpiprazole

Products Brexpiprazole was approved in the United States in 2015 and in the EU and many countries in 2018 in film-coated tablet form (Rexulti). Structure and properties Brexpiprazole (C25H27N3O2S, Mr = 433.6 g/mol) is structurally closely related to aripiprazole (Abilify, generics). Effects Brexpiprazole (ATC N05AX16) has antipsychotic properties. The effects are due to partial agonism … Brexpiprazole

Levomepromazine

Products Levomepromazine is commercially available as film-coated tablets and oral solution (Nozinan). It has been approved in many countries since 1958. Structure and properties Levomepromazine (C19H24N2OS, Mr = 328.5 g/mol) is present in the drugs as levomepromazine hydrochloride or levomepromazine maleate. These are faint yellowish crystalline powders. Levomepromazine maleate is sparingly soluble in water and … Levomepromazine

Lamotrigine (Lamictal)

Products Lamotrigine is commercially available as tablets and dispersible or chewable tablets (Lamictal, generics). It has been approved in many countries since 1994. Vanillin is typically added to the tablets as a flavoring agent and saccharin as a sweetener. Structure and properties Lamotrigine (C9H7Cl2N5, Mr = 256.1 g/mol) is a chlorinated phenyltriazine derivative that was … Lamotrigine (Lamictal)

Terazosin

Products Terazosin is commercially available in tablet form (Hytrin BPH) and has been approved in many countries since 1994. It is no longer registered for the treatment of high blood pressure in many countries (formerly Hytrin), but the indication still exists in other countries. Structure and properties Terazosin (C19H25N5O4, Mr = 387.4 g/mol) is a … Terazosin

Levothyroxine

Products Levothyroxine is commercially available in tablet and capsule form (Eltroxin, Euthyrox, Tirosint). It is also combined fixed with the thyroid hormone liothyronine (T3) (Novothyral). In 2018, an additional solution in monodoses was registered (Tirosint Solution). Bioequivalence is not always given between different preparations. Therefore, switching should be done only under medical supervision. Structure and … Levothyroxine