Lidocaine: Effects, Uses, Side Effects

How lidocaine works Lidocaine is an active ingredient of the Ib antiarrhythmic class, i.e. it suppresses the influx of sodium ions via their channels in the heart. Applied locally, lidocaine also blocks sodium channels and in this way inhibits the sensation and transmission of pain (local anesthetic effect). Antiarrhythmic effect In order to trigger a … Lidocaine: Effects, Uses, Side Effects

Lidocaine: Effects, Uses & Risks

Lidocaine is a drug in the local anesthetic class that also acts as an antiarrhythmic agent. It belongs to the sodium channel blocker group. What is lidocaine? Lidocaine is a drug in the local anesthetic class that also acts as an antiarrhythmic agent. The drug lidocaine was the first amino-amide local anesthetic. It was synthesized … Lidocaine: Effects, Uses & Risks

Mosquito Bites

Symptoms Possible symptoms after a mosquito bite include local reactions such as: Itching Wheal formation, swelling, induration Redness, feeling of warmth Inflammation Due to the skin lesion, there is a risk of infection. Usually mosquito bites are self-limiting and disappear after a few days on their own. However, a mosquito bite can also cause swelling … Mosquito Bites

Antiarrhythmics

Indications For the treatment of cardiac arrhythmias. Active ingredients Class I (sodium channel blockers): class IA: Ajmaline (off-label). Quinidine (out of trade) Procainamide (out of commerce) Class IB: Lidocaine Phenytoin (not approved for this indication in many countries). Tocainide (not commercially available in many countries). Mexiletine (not on sale in many countries). Class IC: Encainid … Antiarrhythmics

Aluminum Lactate

Products Aluminum lactate is commercially available in many countries in combination with lidocaine as an oral spray (Deaftol). Structure and properties Aluminum lactate (C9H15AlO9, Mr = 294.2 g/mol) is the aluminum salt of lactic acid. It consists of the positively charged aluminum ion and three negatively charged lactates (aluminum trilactate). Aluminum lactate exists as a … Aluminum Lactate

Ear Drops

Products In many countries, only a few ear drops are currently on the market. They are also produced in pharmacies themselves. Structure and properties Ear drops are solutions, emulsions, or suspensions containing one or more active ingredients in liquids suitable for use in the ear canal. These include, for example, water, glycols, glycerol, propylene glycol, … Ear Drops

First-Pass Metabolism

The effect of the first liver passage For a perorally administered pharmaceutical agent to exert its effects at the site of action, it usually must enter the systemic circulation. To do so, it must pass through the intestinal wall, the liver, and part of the circulatory system. Despite complete absorption in the intestine, the bioavailability … First-Pass Metabolism

Hemorrhoids Causes and Treatment

Symptoms Hemorrhoids are dilations of the vascular cushions in the anal canal. Possible symptoms include: Bleeding, blood on the toilet paper Pressure discomfort, pain, burning, itching. Unpleasant feeling Inflammation, swelling, skin inflammation. Discharge of mucus, oozing Prolapse, protrusion outside the anus (prolapse). Hemorrhoids can be classified according to various criteria. Common is the classification according … Hemorrhoids Causes and Treatment

Fear of Injections

Symptoms Shortly after an injection, some patients may experience the following symptoms: Pallor Malaise Dry mouth Cold sweat Low blood pressure Drowsiness, dizziness, confusion Nausea Fainting, syncope (short-lasting circulatory collapse). Convulsions (seizures) ECG changes Falls, accidents These disorders occur, for example, shortly after a vaccination, after parenteral administration of drugs, during acupuncture or blood sampling. … Fear of Injections

Mouthwashes

Products Some drugs are commercially available as mouthwashes. A selection of the active ingredients they contain is listed below: Local anesthetics: Lidocaine Disinfectant: chlorhexidine Herbal extracts: chamomile, sage, echinacea, mallow. Anti-inflammatory: benzydamine Antibiotics: Tyrothricin Structure and properties Mouthwashes are liquid dosage forms for the administration of active pharmaceutical ingredients into the mouth and throat. They … Mouthwashes