Nitroglycerin Capsules

Products Nitroglycerin is commercially available in many countries in the form of chewable capsules (Nitroglycerin Streuli). The active ingredient was produced and used medicinally as early as the 19th century. Structure and properties Nitroglycerin or glycerol trinitrate (GTN, C3H5N3O9, Mr = 227.1 g/mol) is an organic nitrate. It is nitrated glycerol. Nitroglycerin exists as an … Nitroglycerin Capsules

Nitroglycerin Patch

Products Nitroglycerin has been approved in many countries since 1981 in the form of a transdermal patch (Nitroderm, others). Structure and properties Nitroglycerin or glycerol trinitrate (C3H5N3O9, Mr = 227.1 g/mol) is an organic nitrate. It is nitrated glycerol. Nitroglycerin exists as an oily liquid and is explosive if not stabilized. Synthesis Effects Nitroglycerin (ATC … Nitroglycerin Patch

Nitroprusside

Products Nitroprusside is available as an infusion preparation in some countries (eg, Nitropress). It was approved in many countries in 2019. Nitroprusside is an old drug, developed in the 19th century and first used medically in the 1920s. Structure and properties Nitroprusside (Na2(Fe(CN)5NO) – 2H2O), Mr = 298.0 g/mol) is present in the drug as … Nitroprusside

Amitriptyline: Tricyclic Antidepressant

Products Amitriptyline is commercially available as film-coated tablets and capsules (Saroten, limbitrol + chlordiazepoxide). It has been approved in many countries since 1961. The distribution of tryptizole was discontinued in 2012. Structure and properties Amitriptyline (C20H23N, Mr = 277.4 g/mol) is present in drugs as amitriptyline hydrochloride, a white powder or colorless crystals that are … Amitriptyline: Tricyclic Antidepressant

Low Blood Pressure

Symptoms Low blood pressure does not necessarily cause symptoms and often remains asymptomatic. Possible symptoms include: Pale and cold skin, cold hands and feet, sweating. Visual disturbances: Blackening in front of the eyes, flickering, parts of the visual field fail Concentration disorders Rapid pulse, palpitations Ringing in the ears Dizziness Weakness, fatigue, lack of performance … Low Blood Pressure

Amisulpride

Products Amisulpride is commercially available as tablets, film-coated tablets, and a drinkable solution (Solian, generic). It has been approved in many countries since 1998. Structure and properties Amisulpride (C17H27N3O4S, Mr = 369.5 g/mol) is a substituted benzamide and a racemate. It exists as a white crystalline powder that is practically insoluble in water. Effects Amisulpride … Amisulpride

Amitraz

Products Amitraz is available in the form of a collar for dogs (Preventic) and as a spray/bath solution or emulsion (Taktic). It is marketed exclusively as a veterinary drug in many countries and has been approved since 1992. Structure and properties Amitraz (C19H23N3, Mr = 293.4 g/mol) is a formamidine derivative and belongs to the … Amitraz

Dopamine Agonists

Products Dopamine agonists are commercially available in the form of tablets, sustained-release tablets, transdermal patches, and injectables, among others. Structure and properties The first active ingredients, such as bromocriptine (Figure), were derived from ergot alkaloids. These are referred to as ergoline dopamine agonists. Later, agents with a nonergoline structure, such as pramipexole, were also developed. … Dopamine Agonists

Frostbite Symptoms and Causes

Symptoms Frostbites are inflamed, superficial, painful, itchy to burning, swollen, reddened to blue-purple skin lesions (patches, papules, plaques). They occur recurrently on both sides, especially dorsally on the fingers and toes. Other exposed areas such as ears, face, nose and thighs may also be affected. Frostbite is most commonly seen in winter and spring. Possible … Frostbite Symptoms and Causes

Furosemide: Drug Effects, Side Effects, Dosage and Uses

Products Furosemide is commercially available in the form of tablets, sustained-release capsules, and as a solution for injection (Lasix, generics). It has been approved in many countries since 1964 and is also used in fixed combination with the aldosterone antagonist spironolactone (Lasilactone, generic). Structure and properties Furosemide (C12H11ClN2O5S, Mr = 330.7 g/mol) exists as a … Furosemide: Drug Effects, Side Effects, Dosage and Uses

Mizolastine

Products Mizolastine was commercially available in tablet form (Mizollen, 10 mg) and approved in many countries since 1996. The tablets are no longer available today. For example, fexofenadine (Telfast) or another 2nd-generation antihistamine can be used as an alternative. Structure and properties Mizolastine (C24H25FN6O, Mr = 432.5 g/mol) a piperidine and benzimidazole derivative. It is … Mizolastine

Glucarpidase

Products Glucarpidase is commercially available in the United States as an injectable (Voraxaze). The drug has not yet been approved in many countries. Structure and properties Glucarpidase is a carboxypeptidase biotechnologically derived from genetically modified. It is protein composed of 390 amino acids and exists as a homodimer with a molecular weight of 83 kDa. … Glucarpidase