Products Laxatives are available in numerous dosage forms. These include, for example, tablets, drops, suppositories, powders, granules, solutions, syrups and enemas. Structure and properties Laxatives do not have a uniform chemical structure. However, groups can be identified (see below). Effects Laxatives have laxative properties. They stimulate bowel emptying by different mechanisms depending on the active … Laxative
Products Macrogol 3350 is commercially available as a powder for making an oral solution (e.g., Transipeg, Movicol, generics). It is included in drugs in combination with salts (potassium chloride, sodium chloride, sodium hydrogen sulfate) but can also be administered without them (e.g., Chung et al., 2009). Macrogol 4000 is also commercially available without salts. In … Macrogol 3350
Products Macrogol 400 is available in pharmacies and drugstores. It should not be confused with macrogol 4000, which is also used as a stool-regulating laxative, among other products. Structure and properties Macrogols are mixtures of linear polymers with the general formula H-(OCH2-CH2)n-OH, indicating the average number of oxyethylene groups. The macrogol type is defined by … Macrogol 400
Products Macrogol 4000 has been approved in many countries since 1987 as granules in combination with salts for bowel emptying and treatment of constipation (e.g., Isocolan). In 2013, a monopreparation that does not contain electrolytes was approved in many countries for the first time (Laxipeg). It is also available without flavoring (pure macrogol). The pure … Macrogol 4000
Products Macrogol 6000 is used as an excipient in many drugs, especially in tablets. Structure and properties Macrogols are mixtures of linear polymers with the general formula H-(OCH2-CH2)n-OH, indicating the average number of oxyethylene groups. The macrogol type is defined by a number indicating the average molecular mass (6000). The substances are very soluble in … Macrogol 6000
Products Macrogols are commercially available in many countries as powders, granules, and as drinking solutions. The agents are available with or without salts (electrolytes). They have been approved since the 1980s. This article refers to pharmaceuticals. Macrogols such as macrogol 400 are also used as pharmaceutical excipients. Structure and properties Macrogols are mixtures of linear … Macrogole
Symptoms Drug therapy with opioids for pain, cough, or diarrhea often results in constipation as an adverse effect. Triggers include, for example, morphine, codeine, oxycodone, tramadol, fentanyl, or buprenorphine. Constipation limits quality of life and can lead to accompanying symptoms and complications such as nausea, vomiting, bloating, abdominal cramps, hemorrhoids, and bowel obstruction. Laxative abuse … Opioids and Constipation
Definition We know from everyday life that the same volumes of different substances do not have the same mass. A liter measure full of down is much lighter than a liter measure filled with sugar. Fresh snow is lighter than ice, and ice is slightly lighter than water, although they are all H2O. Density is … Density
