Products Zolmitriptan is commercially available as film-coated tablets, meltable tablets, and as a nasal spray (Zomig, generics). It has been approved in many countries since 1997. Generic versions entered the market in 2012. Structure and properties Zolmitriptan (C16H21N3O2, Mr = 287.4 g/mol) is an indole and oxazolidinone derivative structurally related to serotonin. It exists as … Zolmitriptan
Products Dihydrocodeine is commercially available as sustained-release tablets, drops, and syrup (Codicontin, Paracodin, Escotussin, Macatussin Syrup). It has been approved in many countries since 1957. Structure and properties Dihydrocodeine (C18H23NO3, Mr = 301.4 g/mol) is a hydrogenated derivative of codeine. It is present in drugs as dihydrocodeine thiocyanate, dihydrocodeine hydrochloride, or dihydrocodeine tartrate. Dihydrocodeine tartrate … Dihydrocodeine
Products Rizatriptan is commercially available in tablet and lingual (melting) tablet form (Maxalt, generics). It has been approved in many countries since 2000. Generic versions went on sale in 2015. Structure and properties Ritatriptan (C15H19N5, Mr = 269.3 g/mol) is present in drugs as rizatriptan benzoate, a white crystalline powder that is soluble in water. … Rizatriptan
Products Mirtazapine is commercially available in the form of film-coated tablets and meltable tablets (Remeron, generics). It has been approved in many countries since 1999. Structure and properties Mirtazapine (C17H19N3, Mr = 265.35 g/mol) is a racemate and exists as a white crystalline powder that is sparingly soluble in water. It is structurally closely related … Mirtazapine: Drug Effects, Side Effects, Dosage and Uses
Products Numerous nasal sprays containing vasoconstrictive agents are commercially available. Among the best known are xylometazoline (Otrivin, generic) and oxymetazoline (Nasivin). In addition to sprays, nasal drops and nasal gels are also available. Decongestants for the nose have been available since the early 20th century (Sneader, 2005). As early as the 1940s, rhinitis medicamentosa was … Decongestant Nasal Sprays
Products Entacapone was commercially available in the form of film-coated tablets (Comtan). It was approved in many countries since 1999. In 2017, distribution was discontinued. A fixed combination with levodopa and carbidopa has also been available since 2004 (Stalevo). Generic versions of the combination drug were approved in 2014. Structure and properties Entacapone (C14H15N3O5, Mr … Entacapon
Products In many countries, no drugs containing amphetamine are currently registered. The active ingredient is subject to narcotics legislation and requires an aggravated prescription, but is basically not prohibited like other substances from the amphetamine group. In some countries, medicines containing dexamphetamine are on the market, for example in Germany and the USA. Structure and … Amphetamine
Products Amphetamines are commercially available as drugs in the form of tablets, sustained-release tablets, capsules, and sustained-release capsules. Structure and properties Amphetamines are derivatives of amphetamine. It is a methylphenethylamine structurally related to endogenous monoamines and stress hormones epinephrine and norepinephrine. Amphetamines are racemates and the –enantiomers. Effects Amphetamines have sympathomimetic, central stimulant, bronchodilator, psychoactive, … Amphetamines
Products In many countries, there are currently no registered medicines containing the active ingredient Cathin. Products containing Cathine are not banned, but are subject to prescription and narcotics laws. Structure D-cathine (C9H13NO, Mr = 151.2 g/mol) is a natural substance from the cath (, Celastraceae), which is also produced synthetically. It is a hydroxylated amphetamine … Cathin
Products Paroxetine is commercially available as film-coated tablets and as a suspension (Deroxat, generic). It has been approved in many countries since 1993. Paroxetine is also marketed as Seroxat and Paxil in some countries. Slow-release paroxetine (CR) is not currently available in many countries. Structure and properties Paroxetine (C19H20FNO3, Mr = 329.4 g/mol) is present … Paroxetine
Products Dextromethorphan is available in the form of tablets, lozenges, sustained-release capsules, syrup, and drops, among others (in many countries, for example, Bexin, Calmerphan, Calmesin, Pulmofor, combination preparations). The first drugs came on the market in the 1950s. Structure and properties Dextromethorphan (C18H25NO, Mr = 271.4 g/mol) was developed as an analog of codeine and … Dextromethorphan
Products The fixed combination Deanxit with the two active ingredients melitracene and flupentixol is commercially available in many countries in the form of film-coated tablets. The drug has been approved since 1973, initially as dragées. The marketing authorization holder is the Danish company Lundbeck. Structure and properties The active ingredients are present in the drug … Melitracene and Flupentixol
