Products The first agent in the GLP-1 receptor agonist group to be approved was exenatide (Byetta) in the United States in 2005 and in many countries and the EU in 2006. In the meantime, several other drugs have been registered (see below). These drugs are also known as incretin mimetics. They are commercially available as … GLP-1 Receptor Agonists
Products Triptans are mainly taken in the form of film-coated tablets and melting tablets. Some are also available as subcutaneous injectable solutions and nasal sprays. Suppositories are no longer commercially available in many countries. Sumatriptan (Imigran) was the first agent in this group to be approved in the United States in 1992 and in many … Triptans: Drug Effects, Side Effects, Dosage and Uses
Structure and properties Many active pharmaceutical ingredients are present in the drug as organic salts. This means that the active ingredient is ionized and its charge is neutralized by a counterion (English ). For example, naproxen is present in the over-the-counter pain reliever as a sodium salt. In this form, it is referred to as … Active Ingredient Salts
Definition and properties The administration or application of a drug refers to its use on the body. The dosage forms (drug forms) used for this purpose consist of the active ingredients and excipients. These include, for example, tablets, capsules, solutions, syrups, injectables, creams, ointments, eye drops, ear drops, and suppositories. Drugs can be liquid, semi-solid, … Administration
Products Aliskiren is commercially available in the form of film-coated tablets (Rasilez, Rasilez HCT + hydrochlorothiazide). It was approved in many countries, in the EU and in the United States in 2007 (Other brand name: Tekturna). Note: Other combination preparations, e.g., with amlodpine (Rasilamlo), are no longer available. Structure and properties Aliskiren (C30H53N3O6, Mr = … Aliskiren
Products Paracetamol is available in suppository form from several suppliers (e.g., Panadol, Acetalgin, Ben-u-ron, Dafalgan, Tylenol). Available dosages include 80, 125, 250, 300, 350, 500, 600, and 1000 mg. Paracetamol suppositories are used primarily in pediatrics, but they can also be given to adults. Structure and properties Paracetamol (C8H9NO2, Mr = 151.2 g/mol) exists as … Paracetamol Suppositories
Products Ibuprofen lysinate is commercially available in the form of film-coated tablets and granules (e.g., Algifor-L, Ibufen-L, generics), among others. It has been approved in many countries since 1979. Structure and properties Ibuprofen lysinate (C19H32N2O4, Mr = 352.5 g/mol) is the salt of the natural amino acid lysine with the analgesic ibuprofen. Ibuprofen is negatively … Ibuprofen Lysinate
Products Ibuprofenarginate is commercially available as film-coated tablets and as granules (Dolo-Spedifen, Spedifen). It has been approved in many countries since 1990. Structure and properties Ibuprofenarginate (C19H32N4O4, Mr = 380.5 g/mol) is the salt of the natural amino acid arginine with the analgesic ibuprofen. Ibuprofen is negatively charged and arginine is positively charged. Ibuprofen is … Ibuprofenarginate
Products Ibuprofen sodium was commercially available in many countries in the form of film-coated tablets (Saridon /-forte). Meanwhile, Saridon contains ibuprofen rather than the sodium salt (Saridon neo). Structure and properties Ibuprofen sodium (C13H21NaO4, Mr = 264.3 g/mol) is the salt of the analgesic ibuprofen with sodium. It exists as ibuprofen sodium dihydrate (2 H2O). … Ibuprofen Sodium
